Job Description

Salary Range:

€46,550.00 - €86,450.00#LI-Hybrid

Location: Menges, Slovenia

Role Purpose:
Our R&D unit in Mengeš is looking for a motivated and highly experienced scientist in field of Mass Spectrometry (MS) and Physical Chemistry Analytics (PCA) to join us and help us develop a diverse portfolio of biotherapeutic modalities.
As a Principal Scientist you must demonstrate a broad and in-depth knowledge of mass spectrometry (MS) technologies and physico-chemical analysis (PCA) to evaluate the developability of various biologics modalities covered by Novartis Biomedical Research and Development units, ranging from traditional antibodies to advanced biologics formats and mixed modalities. You will support cell line development, process optimization, formulation, and material release for in-vivo studies using state-of-the-art methodologies.
You will functionally lead a team of associates where you will be responsible for a continuously strong culture of team spirit and integrity, as well as providing development opportunities for associates on different levels.
We offer a stimulating work environment, ample opportunities for growth and development, and the chance to make a significant impact on the future of medicine. If you are a motivated and talented scientist with a passion for biomedical research, we invite you to apply and become a part of our dynamic team at Novartis.

Naša R&D enota v Mengšu išče motiviranega in zelo izkušenega raziskovalca s področja masne spektrometrije (MS) in fizikalno-kemijske analitike (PCA), ki se nam bo pridružil in nam pomagal razvijati raznolik portfelj bioterapevtikov.

Kot Vodilni raziskovalec I/II morate izkazovati široko in poglobljeno znanje tehnologij masne spektrometrije (MS) in fizikalno-kemijske analize (PCA) za oceno razvijljivosti različnih bioterapevtikov, ki jih pokrivajo Novartisove enote Biomedicinskih Raziskav in Razvoja, od tradicionalnih protiteles do naprednih bioloških formatov in mešanih modalitet. Podpirali boste razvoj celičnih linij, optimizacijo procesov, formulacijo in sproščanje materiala za študije in vivo z uporabo najsodobnejših metodologij.

Funkcionalno boste vodili ekipo sodelavcev, pri čemer boste odgovorni za stalno močno kulturo timskega duha in integritete ter za zagotavljanje razvojnih priložnosti za sodelavce na različnih ravneh.

Ponujamo spodbudno delovno okolje, številne priložnosti za rast in razvoj ter možnost pomembnega vpliva na prihodnost medicine. Če ste motiviran in nadarjen znanstvenik s strastjo do biomedicinskih raziskav, vas vabimo, da se prijavite in postanete del naše dinamične ekipe v Novartisu.

Key Responsibilities:

• Lead and drive the analytical characterization efforts by MS and PCA methodologies of biological formats such as monoclonal antibodies, multispecific antibodies and other therapeutic proteins, transitioning from research to clinical development
• Contribute experimentally to characterize biologics by mass spectrometry including sample preparation, analysis, evaluation, interpretation and reporting
• Prepare and communicate analytical strategies and results at internal and external meetings, as well as in scientific publications if appropriate
• Functionally manage the analytical team and resources, project activities, timelines, maintain a strong customer focus, pro-actively align within global R&D analytics community and set respective objectives for your team
• Provide scientific leadership and clear guidance to the team, optimally leveraging the expertise and experience of individuals
• Drive a culture of collaboration, integrity, and team development, and ensure a safe, empowering, and inspiring working environment

Minimum Requirements - What you will bring to the role

• PhD degree in biochemistry, chemistry, biophysics or a related field with 2 years of experience in pharmaceutical industry, or MSc degree in biochemistry, chemistry, biophysics or a related field with 5 years of experience in pharmaceutical industry

• Strong scientific background in characterization of recombinant proteins by mass spectrometry including experience with modern LC-MS techniques (Intact/reduced/subunit RPMS, peptide mapping, released glycans). Experience with data analysis workflows and report generation.
• Experience with one or more PCA technologies such as liquid chromatography, capillary electrophoresis-based analysis, chip-based technology, calorimetry, viscometry, or light scattering is recommended.
• Proven experience in successfully prioritizing and keeping complex project timelines, excellent organizational skills with the ability to run multiple projects in parallel
• Distinguished team spirit and scientific drive
• High flexibility combined with excellent organizational and communication skills
• Fluency in English (oral/written)

Desirable Requirements:

• Proven ability to lead, coach, and develop people

Skills Desired