Job Description

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people withendocrine diseases and endocrine-related tumors We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture.Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace.This is an exciting time to join Crinetics as we shape our organization into the world’s premierfully integratedendocrine company from discovery to patients. Join our team as we transform the lives of others.

The Vice President, Total Rewards & HR Operations will strategically lead the Compensation, Benefits, and HR Operations functions within the Human Resources department. Reporting to the Chief Human Resources Officer, this role is accountable for evolving Crinetics’ total rewards philosophy and programs to support the company’s continued growth and increasing organizational complexity. This leader will serve as an internal subject matter expert for compensation, benefits, wellness, HR operations, and HR systems; drive scalable, compliant processes and controls; and build a high-performing team and operating model that deliver exceptional employee experience in a complex, multi-state environment.

EssentialJobFunctionsand Responsibilities

Thesemayincludebut are not limitedto:

Strategy & Governance

• Lead all strategic global compensation,benefitsand HR operations processes, including salary planning and administration, variable pay development and administration, benefitswellness programs, annual benefits designopen enrollment, and HRIS/HR operations.

• Create and implement functional strategic plans (3-5 years), associatedbudgetand staffing for the Total Rewards & HR Operations functions.

• Lead and develop a high-performing Total Rewards & HR Operations team

• Serve as a subject matter expert and trusted partner, owning the total rewards philosophy and approach.

• Serve on HR Leadership Team and model leadership for HR function, acting as an enterprise leader across Crinetics

Compensation, Executive & Equity Programs

• Prepare materials for Board of Directors’ Compensation Committee meetings andparticipateasrequiredin collaboration with Finance, Legal, Tax, and external advisors.

• Develop executive offers and continually enhance the offer process in collaboration with Talent Acquisition foroptimaleffectiveness and efficiencyin accordance withTotal Rewards principles.

• Promotepay equity and pay transparency initiatives to strengthen organizational trustandmitigate reputational risk.

• Partner with Stock Administration and other internal partners to manage equity incentives and the Employee Stock Purchase Program (ESPP), driving program effectiveness and enterprise-wide understanding.

Benefits & Wellness

• Lead the design, administration, vendor management, and compliance ofU.S. and international benefits and wellness programs,ensuringcost effectiveness,compliance, andmarketplace competitiveness

• Work in partnership with insurance consultants to ensure compliance with federal, state, and other regulatory agencies and to limit company exposure to liability associated with fiduciary responsibilities.

• Remain current on benefits and employment law changes and trends; proactively recommend actions needed tocomply withU.S. employment laws, governmental agency requirements, fiduciary requirementspertaining toU.S. benefit plans, and international benefits programs as applicable.

HR Operations & HRIS

• Ownthe HR Operationsand HRIS roadmap, driving scalable, compliant processes, strong controls, and high data integrity across the employee lifecycle.

• Lead the use of AI across HR systems to improve workforce planning, personalize rewards, and strengthen insights into engagement and turnover.

• Implement AI/ML solutions to automate HR operations, improve data quality, and increase shared services efficiency.

• Ensure HR operationsand systemscomply withlegal requirements and organizational standards in the pharmaceutical industry.

Policy, Compliance & Market Intelligence

• Develop and implement policies that align with Crinetics’ people strategy and ensure total rewards programs are competitive with market practices and comply with federal and state laws.

• Benchmark across all areas of total rewards to elevate understanding of current and future competitiveness;maintainmarket intelligence on pay transparency, internal equity, and emerging rewards practices.

• Oversee development ofcommunication materials and training to educate managers and employees on totalrewardsphilosophies, programs, and value.

• Facilitate required government reporting, non-discrimination testing,and requiredemployee communications.

• Other duties as assigned.

Education andExperience

Required:

• Bachelor’s degree, with 15+ years of progressive experience in compensation, equity, benefits, and HRIS (An equivalent combination of experience and education may be considered).

• Minimum of 14years’ experience managing and developing people.

• Must have Life Science/Pharmaceutical industry experience.

• Highly preferred to have worked at a fast-paced Biotech or Life Science organization, bringing credibility,energyand enthusiasm to the Human Resources function, founded in sound strategy and long-term success.

• Experience managing HR systems (preferably Workday)anddemonstrateprocess improvements and systems optimization.

• Roll-up-your-sleeves mentality, as this is a senior leadership position but heavily involved in individual contributor work with a desire to buildnext level services.

• Exceptional executive presence and communication skills, with the ability to influence senior leadersand diverse stakeholder groups.

• Experienceoverseeing self-funded and fully funded plans

• Experienceleadingcompensationprograms,utilizingmarket pricing, variable pay, job evaluation, and cost modeling.

• Experience in high-growth environments with the ability to handle shifting priorities and multitasking with tight deadlines.

• Strong business acumen, financially astute, and detail oriented.

• Experience opening global entities and supporting all areas of HR Operations.

• Experience working in public companies and SOX compliance.

• Extensive experience with Microsoft Office Suite coupled with knowledge of executive compensation tools (i.e., Equilar and ISS) and financial tools (e.g., CAP IQ). Experience implementing Workday highly preferred.

• Ability tomaintainconfidentiality and handle sensitive information with absolute discretion.

Preferred:

• SPHR or SHRM-SCP; Certified Comp Professional (CCP) preferred.

Physical Demands and Work Environment:

Physical ActivitiesOna continuous basis, sit atdeskfora long periodof time;intermittently answertelephoneand write or use a keyboard to communicate throughwritten means.Somewalking andliftingupto 25lbs.mayberequiredThe noise level inthe work environment istypically lowto moderateThe physical demands describedabove are representative of those that must be met by an employee to successfullyperform the essential functions andresponsibilities of this jobReasonableaccommodations may be made to enable individualswith disabilities to perform theessential functions and responsibilities.

Travel

You maybe requiredto travel for up to10% of your time.

Equal Opportunity Employer:

Crinetics is proud to be an Equal Opportunity EmployerWe provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws

Salary Range

The salary range for this position is: $300000 - $340000.

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.