Job Description

TranslationalMedicine(TMed)drivesearly clinical development of novel therapeuticsby partneringwith Discovery Sciences and Late-Stage Clinical Researchto translatescientific discoveriesinto human proof-of-conceptandadvancethe most promising candidates through the pipelineto patients Wedesign and execute clinical pharmacology strategiesspanningfirst-in-humanstudiesthrough proof-of-biology/proof-of-conceptandintolate-stage development,supportingworldwide marketingapplicationsand lifecycle management

In a competitive externallandscapeand fast-pacedinternalenvironment, this positionprovidesbothstrategicandoperationalleadership acrossearlyimmunologyprograms,ensuringtimely, high-quality execution of clinical studies and clinical pharmacology strategies worldwideThe successful candidate willtelescope betweenstrategy and hands-onexecution acrossa portfolio of diverse modalities (e.g. peptides, small molecules, biologics), andpartner cross-functionally to develop the neededexpertiseto successfully advance programs to keyinflection pointsin development

Whyjoin us

• Take a leadership role at the intersection of discovery and clinicaldevelopmentto advance novel immunology therapeutics from bench to bedside.

• Influence strategy, build teams, and deliver high-impact clinical programs that shape the future of patient care.

Key Responsibilities:

• Co-ownand execute theearly developmentstrategyfor the immunology portfolio with the Head ofTMedImmunology

• Provide comprehensive strategic planningandoperationaloversightfor immunology clinical programs and trials to ensureefficient,timelyexecutionagainst milestones

• Ensureappropriateresources,competencies, and partnershipsare in place to meetobjectives

• Serve as thedeepsubject matter expertforearlyimmunology clinicaloperations

• Criticallyreviewstrategy andclinical program documents (development plans,investigator’s brochures, protocols,etc.), providingscientific andoperational insight to ensure best path forward

• Partner withBusiness Development and Licensingto evaluate internal and external opportunities that align with portfolio strategy

• Activelyparticipatein annualandquarterly planning cyclesidentifyrisks, developand executemitigation plans, andtrack performance metricsand outcomes

• Ensureimmunology dataintegrityacrossorganization(Book of Business, CTMS, etc.) 

• Build and sustainstrong cross-functional relationships (country operations, clinical supplies, data management, regulatory, etc.)across departments, divisions, and geographies

• Foster the people pipeline: Attract,coach, mentor,andretaintalent;provide performance management support;act as ‘player-coach’ to enrich group skillsets Potential for people management.

• RepresentTMedonenterprisestrategic initiativesand lead continuous-improvement efforts that increase program efficiency and scientific impact 

• Serveas a member of theTMedU.S. Clinical Operations leadership teamandcontributeto shaping department strategy

Education Requirement

• Degree in Life Scienceswith one of the following experience combinations:

• Bachelor’sdegree+≥12 years related experience, OR

• Master’s degree+≥10 years related experience, OR

• Ph.Dor doctorate+≥8 years related experience

• Related ExperienceIncludes:pharmaceuticalindustry roles inclinical drug development, clinical trial management, clinical sitemonitoring/training,medical/regulatory writing, or translational science

Required Experience and Skills

• Proventrack recordbuildingand leadinghigh-performingcross-functional teamsin a matrixedenvironment

• Deep knowledge of early clinical development (Phase 1 and early proof-of-concept)

• Demonstrated ability to collaborate, network, andinfluence peers,senior leaders, and external partners

• Strongoralandwritten communicationskills

• Track recorddelivering results on firm deadlines

• Strong decision-making skills, weighing advantages, disadvantages, and business impact for rapid decisions

• Ability to work successfully with ambiguity and embrace uncertainty

• Experience attracting, developing, andretainingtalent

Preferred Experience and Skills

• Experience leading clinical programsand trialsfor gastroenterology, dermatology,and/orrheumatology, especially autoimmune or immune-mediated disorders, including in both large and small pharma contexts

• Familiarity with broaderpharmaceutical industryconsiderationsand trendsbeyond clinical development

#EligibleforERP

Required Skills:

Clinical Development, Clinical Study Design, Clinical Trial Development, Clinical Trial Management, Clinical Trials, Clinical Trials Operations, Cross-Functional Collaboration, Ethical Compliance, Ethical Standards, Immunology, Stakeholder Engagement

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$190,800.00 - $300,300.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/a

Job Posting End Date:

04/15/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.