Boston Children's Hospital

Staff Scientist

Boston Children's Hospital  •  $94k - $150k/yr  •  Boston, MA (Onsite)  •  9 hours ago
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Job Description

Status

Full-Time

Standard Hours per Week

40

Job Posting Category

Research

Job Posting Description



A Staff Scientist position is available with a flexible start date within the Human Neuron Core at Boston Children’s Hospital. We are looking for an independent and self-motivated scientist to join our team and work on projects utilizing human induced pluripotent stem cell (iPSC)-derived neurons to model neurological disease. The researcher will be responsible for differentiating iPSCs into different subtypes of neurons and glia, as well as phenotyping the neurons using various technologies. Opportunities are available to learn new techniques, including high content imaging and analysis, multi-electrode array recording, and novel genome editing approaches. Qualified candidates should have strong experimental expertise in iPSC tissue culture and neuroscience.


The mission of the HNC is to use human patient-derived neurons to model neuronal disease and provide support for preclinical research by developing tools, assays, and screens to identify novel therapeutics. The HNC is situated at Boston Children’s within the Harvard network, in an environment abounding in experts from neuroscience, neurology, and stem cell biology. We are fortunate as well to be abundantly supplied with many of the best clinicians in the world. Thus, the Staff Scientist will join a fast-paced team that uses cutting edge technology to accelerate therapeutic development for rare neurodevelopmental disorders.

Duties & Responsibilities

  • Tissue culture and quality control of human iPSCs and neuron differentiation
  • Presentations and communication of results to internal and external research groups
  • Independently leading original scientific research projects that can include:
    • Calcium imaging assay development
    • Development of 3D analysis pipelines
    • Differentiation and phenotyping of neurons, including high content imaging and multi-electrode array recordings
    • Assay development and screening
  • Keeping good records, following optimized standard operating procedures, and providing input for improvement in methods to stay up to date with the field
  • Staying up to date with the literature in the relevant fields
  • Mentoring and leading Research Assistants and junior colleagues in the Core
  • Preparing manuscripts for publication

Minimum Qualifications
Education:

  • A master's degree in a STEM-related field in addition 7 years of research experience.

Office/Site Location

Boston

Regular, Temporary, Per Diem

Regular

Remote Eligibility

Onsite Only

Pay Range

$93537.6-$149656 Annual

Boston Children's Hospital

About Boston Children's Hospital

Boston Children's Hospital is a 404-bed comprehensive center for pediatric health care. As one of the largest pediatric medical centers in the United States, Boston Children's offers a complete range of health care services for children from birth through 21 years of age. (Our services can begin interventions at 15 weeks gestation and in some situations we also treat adults.)

We have approximately 25,000 inpatient admissions each year and our 200+ specialized clinical programs schedule 557,000 visits annually. Last year, the hospital performed more than 26,500 surgical procedures and 214,000 radiological examinations.

Our team of physicians and nurses has been recognized by a number of independent organizations for overall excellence, and we're proud to share some notable examples with you here.

Industry
Healthcare & Social Services
Company Size
10,000+ employees
Headquarters
Boston, MA
Year Founded
1869
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