Job Description

The primary function of this position is to conduct translational biomedical research using genetically engineered mouse models, organoid cultures, histology, and omics analyses. Responsibilities include performing and analyzing experiments, troubleshooting technical challenges, interpreting data, and optimizing research protocols. The Staff Associate II will also support project management and inter-laboratory collaborations, applying scientific judgment and technical expertise to advance research projects.

Responsibilities:

Functional Knowledge

• Apply knowledge of regenerative medicine, in vitro organoid and in vivo animal models for translational studies. Integrate experimental findings for mechanistic discoveries and therapeutic evaluations (20%)

Problem Solving

• Troubleshoot and optimize organoid cultures, tissue processing, histologic assays, and related experimental protocols in moderately complex situations. Analyze experimental results to identify technical limitations and recommend protocol modifications or follow-up experiments (20%)

Decision Making/Autonomy

• Conduct assigned research activities independently and collaboratively, including planning experimental workflows, selecting appropriate controls, and adapting protocols based on experimental outcomes. Exercise scientific judgment in prioritizing experiments and coordinating interconnected organoid, animal, and tissuebased studies (20%)

Technical Expertise

• Perform organoid culture, animal tissue collection, histologic processing and examination, IHC/IF, molecular assays, and quantitative and omics-based analyses. Develop and optimize experimental methods for disease modeling, drug screening, and evaluation of therapeutic responses (20%)

Communication

• Summarizes and explains experimental procedures and findings to the PI and research team. Coordinate experimental activities, data, and protocols with collaborating laboratories (20%)

Qualifications

Qualifications

• Bachelor's degree
• 4 years of experience is recommended
• Experience with mouse models, cell and organoid culture, molecular and histologic analyses, and interpretation of experimental data.
• Strong scientific communication and organizational skills, including experience with research presentations, teaching or mentoring, and collaborative research.

Equal Employment Opportunity Statement

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.