AstraZeneca

Senior Scientist, Oncology Bioscience – AI‑Enabled Discovery

AstraZeneca  •  $116k - $174k/yr  •  Waltham, MA (Onsite)  •  10 days ago
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Job Description

This role sits at the intersection of oncology bioscience and applied agentic AIData Science The Senior Scientist will embed AI agentsData Science toolsinto discovery workflows to accelerate hypothesis generation, experimental design, data integration, anddecisionmaking, while sustaining strong biological rigor throughhandsonexperimental execution and interpretation. This is not adatascienceonlyrole; success requires biological understanding combined with practical AI deployment to drive meaningful oncology discovery outcomes.

Key Responsibilities

AIEnabledDiscovery

  • Applyagentic AI systemstodevelopAIagenttoaddress complex oncology R&D questionsand/orfacilitatelab automation process

  • Use AI platforms (e.g.,Claude code,CoScientist) for integrated analysis of phenotypic, signaling, andmultiomicsdata, hypothesis generation, and literature synthesis.

  • TranslateAIdriveninsights into actionable discovery decisions(target validation,LoSpositioning, combination strategies).

  • Clearly communicate AI insights, linking reasoning to biological evidence and program impact.

Oncology Bioscience & Experimental Execution

  • Design, execute, and interpret in vitro oncology assaysto testAIgeneratedhypotheses.

  • Performcellbasedfunctional studies assessing candidate drug activity.

  • Provide biological validation and critical interpretation ofAIdrivenpredictions.

  • Partnercrossfunctionallyto ensure scientific rigor and relevance.

Basic Qualifications

  • BS with 3+ years, MS with 5+ years, or PhD with 1+ years of experience in Oncology, Biology, Data Science, or a related field.

  • Experience developing or applying agentic AI systemsto scientific or R&D problems.

  • Experience using agentic AI platforms for hypothesis generation, data interpretation, or literature synthesis.

  • 2+ years ofhandsonexperience executing and/or overseeing in vitro tumor cell biology studies

  • Expertisein integrated omics data analysis and biological interpretation.

  • Strong data reporting and communication skills aligned to discoverydecisionmaking

Preferred Qualifications

  • Basic coding skills in Python or R

  • Strong collaboration andproblemsolvingskills incrossfunctionalteams.

  • Comfortoperatinginfastmovingenvironments integrating biology, AI, and automation

The annual base salary for this position ranges from $116,284.00 to $174,426.00. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

18-May-2026

Closing Date

28-May-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca

About AstraZeneca

We're transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet. For more information, visit www.astrazeneca.com.

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Industry
Chemicals & Materials
Company Size
10,000+ employees
Headquarters
Cambridge, GB
Year Founded
Unknown
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