【About Astellas】
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. （HP:
Learn more about Astellas）
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
【募集の背景 / Purpose & Scope】
The Senior Research Associate, Process Science, is responsible for activities for new technology development, not related with specific project/programs, but be applicable to current and future clinical trial manufacturing process of our rAAV to support growing and diversifying portfolio of Astellas’ Cell and Gene Therapy Research pipeline. S/he designs and performs experiments mostly by her/his own with some help with colleagues in the team appropriately. S/he makes presentations internally or out side of the company as poster and/or oral presentations to discuss the results of the experiments scientifically.
【職務の内容 / Essential Job Responsibilities】
（雇入れ直後）
- Perform experiments and evaluations of new technologies to enable/maintain Astellas’ place as a leader in rAAV manufacturing with some help if necessary
- Produce scientific data to propose new technologies that meet or exceed target quality profiles, yields, productivity, COGs, and other identified attributes for future manufacture process of rAAV
- Evaluates novel and innovative technology applicable to improve AAV product quality and/or productivity
- Performs design of experiment investigations using software tools for design and data analysis
- Responsible for understanding and applying data generated from experiments and literature used to modify/optimize process parameters
- Assists in the development of robust and cost-effective commercial scale production processes.
- Writes protocols, development reports, and other technical reports to ensure that results are properly archived and communicated
- Ensures safe and compliant laboratory safety procedures are followed
- Regularly presents data, findings and conclusions to program teams and sub-teams
- Proactively collaborates with consultants and internal stakeholders.
（変更の範囲）
会社内での全ての業務
【就業環境に関する要件 / Specific Physical or Environmental Requirements】
• This position is based in Tsukuba Miyukigaoka and will require on-site work.
• This position has responsibilities for advancing new technologies and processes for rAAV manufacturing. This position will be in charge of evaluating new technology development that is tied with some of divisional and/or organizational goals.
• This position reports to the Head of Process Science.
【応募要件 / Qualifications】
＜必須 / Required＞
• Advanced degree in biology or engineering with 3+ years relevant biopharmaceutical industry experience or experience in academia
• Wet lab experience with aseptic technique
• Experience working semi-independently to design and perform scientific experiments to develop and/or evaluate new technologies
• Excellent communication skills
• Able to work in a fast-paced and dynamic environment with competing priorities
• Successful experience working cross-functionally across multiple departments including Research, Manufacturing, and Quality.
• Seeks opportunities to improve existing processes and drive large-scale change that positively impacts organizational success.
• Excellent and effective written, verbal communication and presentation skills.
• Positive, professional attitude with a passion for science.
• Business level English
＜歓迎 / Preferred＞
• Prior rAAV gene therapy experience
• Prior downstream process development experience and/or experience of samples of process development, like ddPCR, ELISA, ultracentrifuge, LC-MS and other analytical devices
• Ability to communicate with colleagues abroad in English
• Experience with authoring IND, CTA, and other related regulatory filings and responding to Agency feedback/inquiries
• Business level Japanese
【応募書類 / Application Documents】
和文履歴書・和文職務経歴書・英文レジュメ
Both Japanese and English Resumes are needed
【選考プロセス / Selection details】
書類選考 → 1次面接 → 最終面接
※変更の可能性もございますので、予めご了承下さい。
CV screening → First interview → Final interview
*Please be advised that there might be a change in the process.
【勤務地 / Location】
（雇入れ直後）
茨城県つくば市 アステラス製薬 つくば研究センター
Tsukuba, Ibaraki
※ＪＲひたち野うしく駅とつくばエクスプレス（TX) 研究学園駅より通勤バスがございます。
（変更の範囲）
会社の定める事業場および自宅
【勤務開始日 / Start Date】
応相談
Will be decided according to the candidate's flexibility
【契約期間 / Contract Duration】
期間の定めなし
Not limited to specified period
【試用期間 / Probation Period】
試用期間原則なし
No probation period in principle
【給与 / Salary】
①基本給：当人の経歴・技術・技能等を考慮して決定
②裁量労働制の場合：裁量労働手当として職務グレードに応じて50,000～100,000円支給
③フレックスタイム制の場合：月間の所定労働時間を超えて勤務する時間に対して時間外勤務手当を支給
①Base salary: will be decided by the candidate's experience, skill and capability.
②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000～100,000yen, based on the Grade)
③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.
【昇給 / Salary Raise】
有り
【賞与 / Bonus】
有り
【諸手当 / Allowance】
裁量労働手当、住宅手当、通勤手当 等
Discretionary work allowance, Housing allowance, Commutation allowance, etc.
【勤務時間 / Working Hours】
8:30～17:30（月～木）、8:30～15:45（金）、専門業務型 裁量労働制
裁量労働制の場合、所定労働時間を働いたものとみなす。
8:30～17:30（Mon～Thu）、8:30～15:45（Fri）
Discretionary Work System
【休日 / Holidays】
完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始
Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays
【休暇 / Vacation Leave】
年次有給休暇、育児休業制度、介護休業制度 等
Annual paid leave, childcare leave system, nursing care leave system, etc.
【福利厚生 / Welfare】
雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等
Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System
【アステラス製薬 採用サイト/ Career web site】
https://re-jp.astellas.com/jp/recruit/newgraduates/
For more information about Astellas, please visit our career web site.
"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."
【What awaits you at Astellas? 】
•Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
•Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
•Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
•A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
【Our Organizational Values and Behaviors】
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
