Job Description

Department Overview

The Department of Pediatrics is recruiting for a new Senior Research Assistant. This position will support a research program focused on identifying oncogenic signaling pathways and therapeutic vulnerabilities in cancer, with an emphasis on kinase-driven mechanisms and translational applications.

Function/Duties of Position

The Senior Research Assistant will lead and execute experimental projects with a moderate to high degree of independence. Responsibilities include designing and performing molecular and cellular experiments, conducting in vivo studies, analyzing and interpreting data, and contributing to manuscripts and grant applications. The individual will also contribute to a collaborative and well-organized laboratory environment, including training junior personnel and supporting efficient research workflows.

The laboratory employs a range of molecular, cellular, and functional perturbation approaches, including CRISPR, RNAi, and small molecule–based strategies, to investigate cancer signaling and therapeutic vulnerabilities.

The ideal candidate is highly organized, detail-oriented, and motivated to contribute to a rigorous and collaborative scientific program. Individuals who thrive in a fast-paced research environment and are excited by discovery-driven and translational science are encouraged to apply.

Required Qualifications

• Bachelor's in biological sciences field or related field AND 1 years of relevant experience OR Equivalent combination of training and experience.
• Strong problem-solving and troubleshooting skills.
• Effective written and verbal communication.
• Ability to manage multiple projects and prioritize competing deadlines.
• Commitment to rigorous record keeping and reproducibility.
• Collaborative, team-oriented mindset.

Preferred Qualifications

• Masters degree in biological science, biochemistry or biomedicine.
• 3 or more years of relevant laboratory experience.
• Experience executing functional perturbation experiments (e.g., CRISPR, RNAi, or small molecule studies).
• Experience with in vivo tumor models and/or pharmacokinetic/pharmacodynamic studies.
• Experience with data analysis, figure preparation, and scientific presentation.
• Prior contribution to manuscripts or grant applications.
• Experience mentoring or supervising learners.

Additional Details

• Location of employment is within a mammalian cell culture, biochemistry and molecular biology research lab.
• Work involves possible exposure to viral vectors (retroviral and lentiviral), non-replicating infetious viral particles, malodorous vapors, toxic chemicals and acids, presence of carcinogenic substances and human and animal tissues and fluids, including whole animals.

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Why apply to OHSU?

We are Oregon's only public academic health center. In addition to caring for patients, we lead groundbreaking research. We also train the next generation of health care professionals. As Portland's largest employer, we give you opportunities to learn and advance in a system of hospitals and clinics across Oregon and Southwest Washington. All are welcome. OHSU welcomes people of all ages, ethnicities, genders, national origins, religions and sexual orientations. We are striving to build an anti-racist, multicultural institution and encourage people with diverse backgrounds to apply. To request reasonable accommodation, contact askhr@ohsu.edu