Vertex is seeking a Sr. Principal AI Engineer, Agentic AI Platform to design, build, and optimize the shared platform capabilities that power AI-enabled products and intelligent workflows across the enterprise. This role will focus on delivering production-grade platform services for model integration, prompt and workflow orchestration, evaluation, observability, performance optimization, and agent lifecycle management.
A key focus of this role will be enabling a build/bring-your-own-agents capability within the Agentic AI Platform, allowing teams across Vertex to create, integrate, customize, and operationalize their own agents using shared platform standards, tooling, and governance controls.
The ideal candidate combines strong software engineering fundamentals with deep experience in applied AI systems. This individual will be comfortable operating across rapid experimentation and engineering rigor, translating emerging AI capabilities into scalable, reliable, secure, and reusable platform components. The Senior Principal AI Engineer will play a critical leadership role in accelerating AI adoption across Vertex by enabling product teams to build and deploy AI solutions faster and more effectively.
Key Responsibilities
Required Qualifications
Technical Skills Required
Preferred Skills
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Pay Range:
$188,000 - $282,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and have made significant advancements in multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continue to progress clinical and research programs in these diseases. We also have a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where we have deep insight into causal human biology, including acute and neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy, autosomal dominant polycystic kidney disease, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency.
Our global HQ is in Boston, and we have research and development (R&D) sites and commercial offices worldwide.
Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. We have also earned a spot on TIME Most Influential Companies, TIME Best Inventions, and Fast Company Most Innovative Companies lists. Our research and medicines have received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the Prix Galien, the Scrip Award and the Breakthrough Prize awards.
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