Alexion Pharmaceuticals, Inc.

Senior Manager - Network Supply Planning

Alexion Pharmaceuticals, Inc.  •  Ireland (Onsite)  •  1 day ago
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Job Description

This Senior Manager, Network Supply Planning is part of the Global Supply Planning Organisation and has responsibility for planning a group of resources (internal or external).

Location: Dublin, Cork, or Athlone (3 days per week in the office)

The role creates, develops and maintains a cross-brand supply & capacity plan for assigned resources / products, while facilitating efficient manufacturing operations for tactical horizon, according to monthly planning cycle.

This role drives the S&OE process by facilitating the relevant meetings and reviews on a weekly / monthly basis. The role is a key player in the S&OE process by leading the supply consensus meeting with sites, by providing necessary insights to support decision making.

This role is the gate keeper of the operational plan and liaison between manufacturing locations and the commercial supply chain team (governed by S&OE). Finally, the role ensures that executable supply plans are seamlessly handed over manufacturing locations internally and externally.

Key Responsibilities

· Supply execution across the network: Coordinate day-to-day plan execution across internal sites and CMOs, ensuring OTIF service at or above target and continuity of patient supply.

· S&OE facilitation: Run brand S&OE meetings to review demand, supply, and inventory; surface risks and recommend actions aligned to in-market targets and product monograph constraints.

· KPI tracking and reporting: Maintain and report core KPIs (Production and release adherence, service level, backlog, OTIF, inventory value/MOH). Providing regular performance updates and action-oriented insights to senior stakeholders.

· Inventory management (DS/DP/FP): Manage short-horizon inventory targets across drug substance, drug product, and finished product; position stock to unlock efficient planning and production while minimizing write-offs.

· OMP master data: Implement and maintain product parameters and master data in OMP to drive replenishment and inventory at decoupling points and in market; ensure data quality and governance.

· Batch allocation and compliance: Execute batch allocation per base plan, regulatory approvals, and monograph requirements; execute management of ring-fenced inventory where needed and maintain audit-ready documentation.

· Capacity plan updates: Update site capacity plans monthly; align with manufacturing and external partners to reflect demand, yield, and lifecycle changes.

· Supply issue management: Anticipate and mitigate supply risks (capacity, yield variability, QA/QC release timing, regulatory events); coordinate cross-functional problem-solving and follow agreed escalation paths.

· Escalation and hypercare coordination: Initiate and support escalations and hypercare when patient supply risk is identified; drive timely recovery actions across functions.

· Inventory risk management: Systematically identify inventory risk and drive mitigation actions to avoid obsolescence risk.

· Continuous improvement and digital enablement: Contribute to automation of reporting and scenario planning; support adoption of advanced planning tools and data accuracy improvements.

· Plan Handover to sites: Ensures that constrained executable plans are seamlessly handed over to manufacturing sites.

· Scenario Planning: Responsible for developing & executing resource scenario’s to support supply decisions.

Preferred Capabilities and Skills

· Broad & deep supply chain management experience gained in a manufacturing and above site supply chain setting.

· Analytical & ability to interpret large amounts of data and find & frame the critical problems (not over-reacting or reacting on the wrong escalations and getting to root cause).

· Partnering and Collaboration - Encouraging and building mutual trust, respect, and collaboration among stakeholders.

· Building strong relationships with site operations management and planning teams while respecting the overall network optimization objectives

· Collaborative problem solver- understanding the overall network supply and demand dynamics, able to define the required options to remediate supply issues and assess feasibility and trade-offs of proven and unproven proposals

· Proactive mindset -- Analysing information and evaluating results to choose the best solution and solve problems early in the process by identifying root cause and implementing corrective and preventative actions

· Strong Communicator & Influencer - confident in presenting to and communicating with stakeholders and peers at all levels of the organization in an efficient and effective way in written form, e-mail, or in person.

· Effective risk manager - scenario planning and trade off management – ensuring stable supply outlook

· Adaptable and resilient

Qualifications

· Experience: 6-8 years in pharmaceutical/biopharma/medical devices/FMCG experience, experience in supply planning, logistics, order management, production scheduling desirable.

· APICS / CSCP or equivalent certification desirable

· Lean certification desirable

Date Posted

29-May-2026

Closing Date

11-Jun-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Alexion Pharmaceuticals, Inc.

About Alexion Pharmaceuticals, Inc.

Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community. We are driven by a mission to change what it means to live with a rare disease.

A leader in rare disease for more than three decades and today continues to build a diversified pipeline across disease areas with significant unmet need, using an array of innovative modalities.

As part of AstraZeneca, Alexion is continually expanding its global geographic footprint to serve more rare disease patients around the world. It is headquartered in Boston, US.

Alexion’s pioneering legacy in rare disease is rooted in being the first to translate the complex biology of the complement system into novel medicines. Alexion pushes boundaries to accelerate discovery of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the world and continues to expand its reach to benefit more people globally.

GL/NP/0116

GL/NP/0095

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Industry
Biotech & Life Sciences
Company Size
5,001-10,000 employees
Headquarters
Boston, Massachusetts
Year Founded
1992
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