Job Description

Key Responsibilities

• Design, plan, and perform in-vivo experiments to evaluate the efficacy and safety of small molecule/biologics drug candidates.
• Analyse and interpret complex biological data to Hit/Lead selection and optimization.
• Develop and validate in-vivoin-vitro model systems for evaluation of NCE’s.
• Collaborate with multidisciplinary teams including synthetic chemists, bioinformatics, pharmacokinetic scientist, molecular biologist and external CROs to drive project goals.
• Utilize statistical tools to support data analysis and compound optimization.
• Prepare detailed reports, technical summaries, and presentations.
• Stay updated with current scientific literature and advancements in drug discovery methodologies and technologies.
• Contribute to the preparation of scientific publications, patent applications, and regulatory documentation as needed.

Knowledge/Skills/Abilities

• PhD freshers or 1-2 years or master’s with 3-8 years of industry experience in immuno-oncology, pharmacology, biology, or a related field.
• Proven experience in drug discovery and development with small molecules/biologics.
• Experience with in-vivo pharmacology studies in the disease area of oncology.
• Strong knowledge of biochemical, cell-based, and analytical assay techniques.
• Excellent problem-solving, and organizational skills.
• Strong communication skills, both written and verbal.
• Expertise in designing and executing experiments for drug efficacy.
• Ability to interpret complex scientific data to guide drug optimization.
• Proficiency in establishing and validating experimental models.
• Collaborative mindset with the ability to work effectively in multidisciplinary teams.
• Commitment to scientific rigor, innovation, and continuous learning.

Required Technical Skills

In-vivo Skills

• Expertise in animal handling includes sampling and dosing by different routes (IP, IV, PO)
• Plan and execute mouse tumor models like Xenograft
• Expertise in tissue processing and in-vitro/ex-vivo assay techniques

Data Analysis/Documentation

• GraphPad Prism or equivalent statistical software
• Data interpretation and report preparation
• Contribute to internal research updates, publications, and regulatory documentation.

Preferred Skills

• Experience in immuno-oncology models
• Knowledge of tumor microenvironment biology
• Experience with biomarker analysis

Amneal is an equal opportunity employer. We do not discriminate based on caste, religion, gender, disability, or any other legally protected status. We believe in fostering a workplace that values diversity and inclusion.