Mirum Pharmaceuticals, Inc.

Senior Director, International FP&A

Mirum Pharmaceuticals, Inc.  •  Zug, CH (Hybrid)  •  11 days ago
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Job Description

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

Reporting to the Executive Director of FP&A (based in US), the Senior Director, FP&A – International will lead and own the financial planning and analysis function for Mirum’s International Commercial Operations. Based in Zug, this role serves as the primary finance partner to International leadership, with full accountability for financial performance, planning, and strategic decision support across Europe and expanding global markets.

This individual will play a critical role in building and scaling the international finance capability to support the commercialization of LIVMARLI and future pipeline assets. As a core member of the International leadership team, the role will drive financial visibility, inform strategic decisions, and ensure alignment between regional execution and global corporate objectives.

This position combines strategic leadership with hands-on execution in a dynamic, growth-stage biotech environment and requires close collaboration with Commercial, Market Access, Supply Chain, R&D, Legal, Compliance, HR, and global Finance teams.

JOB FUNCTIONS/RESPONSIBILITIES

International Commercial Finance Leadership

  • Own and lead FP&A for International Commercial Operations, with full accountability for regional P&L performance
  • Serve as the primary finance partner to International leadership, influencing strategy, investment decisions, and operational execution
  • Act as a bridge between International markets and US headquarters, ensuring alignment with global financial goals and expectations
  • Build and evolve the international FP&A capability, including processes, tools, and team structure over time

Planning, Forecasting & Performance Management

  • Lead the annual planning process, long-range planning, and ongoing forecasting cycles for International markets
  • Partner cross-functionally to develop robust, data-driven forecasts, challenging assumptions and identifying risks and opportunities
  • Drive monthly and quarterly business reviews, delivering clear insights into performance drivers and actionable recommendations
  • Ensure timely and accurate financial reporting, translating results into meaningful business insights for leadership

Strategic Decision Support & Growth

  • Lead scenario planning and financial modeling to support key business decisions, including market expansion, product launches, and resource allocation
  • Evaluate investment opportunities through ROI analysis, supporting prioritization of high-impact initiatives
  • Partner with Commercial and regional teams to optimize resource deployment and maximize return on investment
  • Support launch planning for new products and geographic expansion, including financial modeling and risk assessment

Pricing, Market Access & Profitability

  • Partner with Market Access to support pricing strategy and governance, balancing access considerations with profitability objectives
  • Conduct pricing and sensitivity analyses to inform key decisions across markets
  • Develop a deep understanding of market dynamics, including competitive landscape, reimbursement environments, and access constraints
  • Identify and drive margin improvement opportunities through pricing, cost optimization, and strategic trade-offs

Operational Excellence & Process Improvement

  • Drive enhancements in financial planning processes, data quality, and reporting capabilities
  • Support the implementation and optimization of FP&A systems and tools to enable scalable growth
  • Establish and standardize best practices across markets while accommodating local market nuances
  • Navigate financial complexities across multiple jurisdictions, including FX exposure and evolving market conditions

Leadership & Stakeholder Management

  • Influence and collaborate with senior stakeholders across geographies and functions
  • Present financial insights and recommendations to executive leadership and global finance teams
  • Foster strong partnerships across International Commercial, ensuring finance is embedded in decision-making
  • Contribute to building a high-performance, collaborative, and accountable culture within the organization

QUALIFICATIONS

Education /Experience:

  • 12–15+ years of progressive experience in FP&A or finance, with significant exposure to global or international operations
  • Prior experience in biotech, pharmaceuticals, or life sciences strongly preferred, particularly in commercial-stage environments
  • Demonstrated experience supporting international markets, including product launches and market expansion
  • Strong financial modeling, forecasting, and strategic planning capabilities
  • Proven ability to influence senior stakeholders and operate as a strategic business partner
  • Experience working in complex, multi-country environments with an understanding of market access and pricing dynamics
  • Ability to thrive in a fast-paced, high-growth environment with evolving priorities

#LI-HYBRID

Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.

Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.

Mirum Pharmaceuticals, Inc.

About Mirum Pharmaceuticals, Inc.

Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare diseases affecting children and adults. Mirum has three approved medications: LIVMARLI® (maralixibat), CHOLBAM® (cholic acid) capsules, and CTEXLI™ (chenodiol) tablets.

LIVMARLI, an IBAT inhibitor, is approved for the treatment of two rare liver diseases affecting children and adults. It is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the U.S. (three months and older), in Europe (two months and older), and in other regions globally. It is also approved in the U.S. in cholestatic pruritus in PFIC patients 12 months of age and older; in Europe, it is approved for patients with PFIC three months of age and older. Mirum is also initiating the Phase 3 EXPAND study, a label expansion opportunity for LIVMARLI in additional settings of cholestatic pruritus. CHOLBAM is FDA-approved for the treatment of bile acid synthesis disorders due to single enzyme deficiencies and adjunctive treatment of peroxisomal disorders in patients who show signs or symptoms of liver disease. CTEXLI is FDA-approved for the treatment of cerebrotendinous xanthomatosis (CTX) in adults.

Mirum's late-stage pipeline includes two investigational treatments for several rare diseases. Volixibat, an IBAT inhibitor, is being evaluated in two potentially registrational studies including the Phase 2 VISTAS study for primary sclerosing cholangitis (PSC) and Phase 2b VANTAGE study for primary biliary cholangitis (PBC). Volixibat has been granted Breakthrough Therapy Designation for the treatment of cholestatic pruritus in patients with PBC. Mirum is also planning for a Phase 2 study evaluating MRM-3379, a PDE4D inhibitor for the treatment of Fragile X syndrome, a rare genetic neurocognitive disorder.

Industry
Chemicals & Materials
Company Size
201-500 employees
Headquarters
Foster City, CA
Year Founded
2018
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