Job Description

Cambridge, US; Gaithersburg, US; New Jersey, US | full time | Job ID: 11168

About the Role:

As a Senior Director, Biostatistics, you will play a pivotal role in shaping the statistical strategy for our clinical programs, driving data-driven decisions that are integral to BioNTech’s mission of advancing global health. Your expertise will contribute to the development of innovative therapies, helping us address unmet medical needs in oncology and beyond.

You will work within a collaborative environment, partnering with multidisciplinary teams to ensure statistical excellence across all phases of clinical trials. This is your opportunity to lead impactful projects while mentoring talented professionals and influencing regulatory submissions.

Your Contribution:

• Represent Biostatistics in cross-functional clinical study teams and provide expert guidance on statistical aspects
• Lead statistical strategies for trials within a platform or portfolio, ensuring high-quality deliverables
• Develop statistical analysis plans, perform sample size calculations, and validate analysis results
• Oversee outsourced statistical CRO activities while ensuring quality and timely delivery
• Provide statistical insights into clinical development plans, protocols, reports, regulatory submissions, and publications
• Support health authority meetings by preparing documents and responses as required
• Mentor and manage biostatistics staff while fostering talent development

A Good Match:

• Advanced degree (PhD or Master’s) in (Bio)Statistics, Mathematics, or equivalent field
• Extensive experience (12+ years for PhD; 15+ years for Master's) in the pharmaceutical industry or CRO
• Proven leadership experience managing biostatistics teams and collaborating in matrix organizations
• Expertise in planning, conducting, and analyzing oncology trials across phases I-IV
• Proficiency in SAS/R software and sample size calculation tools like EAST or NQuery
• Strong knowledge of advanced statistical methods (e.g., adaptive design or Bayesian approaches)
• Experience in leading to answer health authority questions (FDA, EMA) and leading in statistics on regulatory submissions, including developing ISE/ISS packages.
• Exceptional analytical skills with the ability to develop realistic plans and communicate complex analyses effectively

Expected Pay Range: $198,900/year to $312,400/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). *Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

Your Benefits:

BioNTech is committed to the wellbeing of our team members and offers a variety of benefits in support of our diverse employee base. We offer competitive remuneration packages which is determined by the specific role, location of employment and also the selected candidate’s qualifications and experience.

Note: The availability, eligibility and design of the listed benefits may vary depending on the location. The final requirements for the individual use of our benefits are based on the company's internal policies and applicable law.

How to apply:

Apply now by sending us your application documents including Curriculum Vitae, copy of ID, copies of degree certificates and professional certificates, motivation letter as well as your contact details via our online form.

Please note:

Only applications sent via our online form shall be considered. By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.

We are looking forward receiving your application.