Job Description

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?”That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

The Senior Director – Assistant Controller is responsible for supporting the Controller in ensuring the integrity of the Company’s financial information through compliance with U.S. GAAP, SEC reporting requirements, and Company policies and procedures. This role oversees all core accounting operations, and ensures timely and accurate financial reporting, a disciplined month-end close process, and a strong internal control environment. The Senior Director – Assistant Controller leads key accounting functions including general ledger, operating expenses, accruals, prepaids, cash, payroll accounting, fixed assets, leases, cost accounting, consolidations, intercompany, and technical accounting implementation. This leader will drive process improvements, scalability, and automation to support a growing public company environment. This role partners closely with Finance, Internal Audit, IT, Legal, HR, and other cross-functional teams to support financial transparency, operational excellence, and regulatory compliance.

Job Responsibilities

• Lead and manage the monthly, quarterly, and annual close processes for all accounting areas
• Ensure timely and accurate preparation and review of journal entries, account reconciliations, and supporting schedules
• Oversee consolidations, intercompany eliminations, and general ledger integrity
• Maintain a disciplined close calendar and continuously improve close efficiency
• Partner with SEC Reporting to ensure completeness and accuracy of financial information supporting external filings
• Support technical accounting implementation and new accounting standards adoption
• Oversee accounting for operating expenses, accruals, prepaid assets, fixed assets, leases, cost accounting, cash, and payroll
• Review complex accounting transactions and significant estimates
• Ensure proper balance sheet management and reconciliation discipline across all assigned areas
• Oversee payroll accounting, including related compliance and audit support
• Implement and enhance internal controls over financial reporting (first year SOX compliance)
• Partner with Internal Audit and external auditors to support quarterly reviews and annual audits
• Ensure appropriate documentation of policies, procedures, and accounting positions
• Proactively identify control gaps and implement remediation plans
• Lead accounting process optimization and automation initiatives
• Partner with IT and Finance on ERP enhancements and system implementations
• Collaborate with other departments such as legal, compliance, HR, etc. in process improvement and standardizing procedures
• Develop scalable processes to support company growth and operational complexity
• Establish KPIs and metrics to monitor accounting performance and efficiency
• Lead, develop, attract and hire accounting leaders and team members across assigned functions
• Establish clear accountability, performance expectations, and development plans
• Foster a culture of ownership, continuous improvement, and collaboration

Required Qualifications

• Bachelor’s degree in Accounting or related field
• CPA required
• 12+ years of progressive accounting experience, including a combination of public accounting (Big 4 preferred) and public company experience
• 5+ years of leadership experience managing managers and cross-functional teams
• Strong experience in U.S. GAAP and SOX compliance within a public company environment
• Demonstrated experience leading and improving the month-end close process
• Strong ERP systems experience; involvement in system implementations or upgrades preferred
• Advanced proficiency in Microsoft Office Suite, particularly Excel

Preferred Qualifications

• Experience in life sciences, healthcare, diagnostics, or other regulated industries
• Experience scaling accounting operations in a newly-public, high-growth environment
• Strong technical accounting background.

Physical Demands

• Must possess ability to sit and/or stand for long periods of time
• Must possess ability to perform repetitive motion

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• At times may be required to work weekends/holidays.

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.