Job Description

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Digital Product Strategy and Innovation Manager (AI)

What you will do

Let’s do this. Let’s change the world. We are seeking a Senior Digital Product Manager, to join the AI & Data Lab Product Management Team. This role will lead the identification, evaluation, and validation of high-potential AI and data-driven opportunities across Amgen, shaping strategic opportunities and providing evidence-based recommendations that inform enterprise investment and scaling decisions.

The Senior Digital Product Manager will establish product discovery and validation approaches that enable Amgen to determine where AI can create meaningful business and patient value, where opportunities warrant further investment, and where initiatives should be redirected, paused, or stopped.

Operating at the intersection of business strategy, AI product innovation, data, technology, and enterprise transformation, this role will provide strategic product leadership across ambiguous, cross-functional opportunities and influence senior business and technology stakeholders on product direction, prioritization, investment, and scale.

Responsibilities:

• Lead the identification, framing, prioritization, and validation of a variety of AI-enabled business opportunities across Amgen, ensuring resources and validation efforts are focused on opportunities with the greatest potential enterprise value and strategic alignment.
• Evaluate whether proposed AI opportunities have the right data foundations, system integrations, architecture patterns, model capabilities, security controls, and operational support needed to move from concept to scalable solution.
• Collaborate with data scientists, ML engineers, data engineers, software engineers, solution architects, platform teams, and cybersecurity partners to shape solution concepts, understand technical tradeoffs, and identify dependencies early in the validation process.
• Design and execute rapid discovery sprints, prototypes, pilots, user research, and experiments to assess desirability, feasibility, viability, value, and risk. Use evidence to determine whether opportunities should advance, pivot, pause, or scale.
• Assess how LLMs, AI agents, machine learning models, NLP, automation, knowledge retrieval, analytics, and intelligent workflow tools can improve productivity, decision quality, scientific discovery, operational efficiency, and workforce effectiveness.
• Develop product requirements that account for user experience, data availability, model performance, output quality, explainability, reliability, latency, integration needs, governance, and ongoing measurement.
• Synthesize findings from validation work into clear product recommendations, opportunity briefs, technical feasibility assessments, business cases, and executive-ready narratives.
• Provide senior leaders with clear, evidence-based recommendations on investment, prioritization, scaling, and termination decisions, including explicit articulation of tradeoffs, uncertainties, dependencies, and risks.
• Own and actively manage a portfolio of AI opportunities across discovery, prototype, pilot, and scale-readiness stages, balancing strategic value, feasibility, risk, resource requirements, dependencies, and organizational readiness.
• Ensure validation efforts consider responsible AI, data privacy, model risk, cybersecurity, compliance, regulatory considerations, human oversight, change management, and enterprise scalability from the earliest stages of discovery.
• Lead executive and cross-functional decision forums that align business, scientific, technology, data, security, and governance stakeholders around opportunity priorities, product direction, technical tradeoffs, investment decisions, and paths to scale. Navigate competing perspectives and drive clarity and decisions in ambiguous or high-impact situations.
• Translate Amgen business and transformation priorities, emerging AI capabilities, technology strategy, and portfolio learnings into strategic product opportunity areas, identifying where reusable capabilities, platforms, data assets, or common patterns can create value across multiple functions rather than through isolated point solutions.
• Provide product leadership, coaching, and thought partnership to product managers and cross-functional teams, helping raise the maturity of AI product discovery, experimentation, evidence-based decision making, and product management practices across the organization.
• Act as a thought leader for AI product management, bringing external product, technology, and industry perspectives into Amgen and translating emerging AI capabilities into practical implications for enterprise product strategy.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Senior Digital Product Manager professional we seek has these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Information Systems, Technology, Product, Digital, AI, Data, Business Transformation, or related experience

OR

Master’s degree and 6 years of Information Systems, Technology, Product, Digital, AI, Data, Business Transformation, or related experience

OR

Bachelor’s degree and 8 years of Information Systems, Technology, Product, Digital, AI, Data, Business Transformation, or related experience

OR

Associate’s degree and 10 years of Information Systems, Technology, Product, Digital, AI, Data, Business Transformation, or related experience

OR

High school diploma / GED and 12 years of Information Systems, Technology, Product, Digital, AI, Data, Business Transformation, or related experience

In addition to meeting at least one of the above requirements, you must have a minimum of 2 years of experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources. Your managerial experience may run concurrently with the required technical experience referenced above.

Preferred Qualifications:

• 4+ years of product management, product strategy, innovation, consulting, digital transformation, or related experience.
• 2+ years of experience with AI, machine learning, data products, automation, LLMs, agents, NLP, analytics, or enterprise AI solutions.
• Demonstrated ability to operate effectively in high-ambiguity environments, independently frame complex problems, make sound recommendations with incomplete information, and drive alignment across stakeholders with competing priorities.
• Demonstrated experience leading AI or data products through discovery, validation, investment decision, and scale.
• Familiarity with generative AI, LLMs, retrieval-augmented generation, AI agents, prompt engineering, model orchestration, NLP, predictive analytics, or intelligent automation.
• Understanding of data architecture concepts, including data pipelines, data lakes, data warehouses, APIs, metadata, master data, data governance, and data quality.
• Experience shaping product strategy and investment decisions involving enterprise AI platforms and capabilities.
• Demonstrated ability to lead cross-functional product decisions across business, engineering, architecture, data, security, and governance teams.
• Experience establishing and leading product discovery and experimentation approaches across multiple complex initiatives.
• Ability to evaluate AI opportunities across desirability, feasibility, viability, value, risk, scalability, and data readiness.
• Experience developing business cases, opportunity assessments, technical feasibility summaries, executive narratives, or investment recommendations.
• Familiarity with biotech, pharmaceutical, R&D, manufacturing, medical, or enterprise business workflows.
• Demonstrated ability to influence senior executives and drive decisions through clear product narratives, recommendations, and evidence.
• Hands-on ability to analyze user feedback, usage data, workflow metrics, model outputs, experiment results, or AI product performance.
• Comfort working in fast-paced, cross-functional environments where priorities evolve quickly.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

Salary Range

170,958.80USD -231,297.20 USD