We are currently seeking a full- or part-time (min. 32 hrs/ week) Senior Clinical Operations Lead* to strengthen our Clinical Trial Leadership team. You will work in Tübingen, Munich or remote within Germany in an interdisciplinary environment with colleagues from Germany and the US and will contribute to our mission of delivering novel PRAME immunotherapies to patients with cancer.
YOUR MISSION
Your main responsibilities will include but are not limited to the following tasks:
Ensure and support GCP-compliant planning and execution of clinical studies within Clinical Operations, including provision of study cost information and regular updates impacting global timelines and budgets
Oversee GCP-compliant monitoring of outsourced Clinical Operations activities, conduct regular meetings, and escalate issues as needed
Contribute to the selection and qualification of GCP/GCLP vendors within clinical outsourcing, and take responsibility at study level for feasibility assessments, site selection, risk and issue management, matrix coordination, and collaboration with internal and external stakeholders
Lead project reviews, manage processes, and escalate key issues, proposing appropriate solutions or mitigation strategies
Manage Clinical Operations vendors and support the Vendor Governance team through feedback and collaboration
Provide operational support to central laboratories
Perform administrative clinical trial tasks (finance, logistics, and communication), ensure assignment and completion of study-related training, develop and maintain SOPs and training materials, and mentor less experienced Clinical Operations Leads upon request
YOUR PROFILE
You hold at least a Master’s degree, preferably in life sciences or a related field, and bring 6+ years of experience in clinical project management within the pharmaceutical or biotech industry, ideally in oncology and cell therapy. You feel comfortable in a matrix environment and are passionate about managing clinical studies.
We expect a high level of assertiveness, enabling you to drive topics forward, make decisions, and stand by them. You think pragmatically and maintain a clear view of the bigger picture while ensuring effective execution. You act proactively in fast-paced environments, take ownership, and consistently push projects to completion in a structured, results-oriented way. A fluent and clear communication in German and English (at least C1-level) and effective collaboration skills complete your profile.
WHY US?
We are the global leader in precision targeting of PRAME. Driven by our mission to make an impact on the lives of patients with cancer, we are a committed and inspired team and cherish the collegial, highly motivated, and family-friendly atmosphere within Immatics. Our culture allows for a high level of originality, independent thinking, and initiative. We believe in supporting our employees’ professional and social skills: We enable them to join conferences and trainings as well as to enjoy our Immatics benefits – e.g., job bike, job ticket, Health Programs, childcare benefits, relocation allowance, Company summer and winter events.
NOTICE
*We value diversity and inclusion. Immatics N.V. and all Immatics subsidiaries are equal opportunity employers that evaluate qualified applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
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