Job Description

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Our toolkit of RNA-targeting modalities including RNAi silencing and RNA editing provides us with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. Our diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and includes clinical programs for Duchenne muscular dystrophy and Huntington’s disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Driven by the calling to “Reimagine Possible”, we are leading the charge toward a world in which human potential is no longer hindered by the burden of disease.

Wave Life Sciences USA seeks a highly motivated Discovery IT Business partner to join our Information Technology team in Cambridge and Lexington Massachusetts. This role partners with all areas of Discovery to drive new technology & automation solutions, expand current Discovery Informatics capabilities and ensure operational excellence. This individual will participate in an agile based, team-oriented, fast-paced, and cross-disciplinary biotech/IT environment. This role is a great opportunity at the intersection of Discovery, Data Science, and IT to contribute to building a vision for the Wave lab of the future. This position will report to the Senior Director, Discovery IT and will be a key member of the IT operations team, DS/IT steering committee and various SONAR (Wave’s Discovery Informatics Platform) teams.

Experience

• Undergraduate degrees in Information Management/Technology, Computer Science required. Graduate degrees and/or Discovery Science degrees (Chemistry, Biology) highly preferred.
• Minimum 7 years’ experience in Pharmaceutical/Biotech companies; 5 years’ experience working in Discovery required.
• Minimum 5-8 years’ experience as an IT business analyst or R&D product specialist required.
• Experience with Discovery systems including eLNB, compound registration, pipeline tools, inventory management and lab automation required.
• Experience leading projects and/or Discovery business teams required.
• Working knowledge of FDA, EMA regulations such as Annex 11, 21 CFR Part 11, Part 210, 211; Computer Systems Validation and GAMP framework required.

Responsibilities

May include some or all of the following:

• IT Business Partner for Biology, Data Sciences, Lab Systems, Medicinal Chemistry, Translational, Research Pharmacology, Process Development Preclinical and Process Engineering.
• Product owner for critical lab informatics systems (Dotmatics, CLIMB, Lab Voice) managing the full lifecycle from initial requirements gathering through production deployment, operations, updates, minor and major upgrades and retirement.
• Lead new Discovery technology projects including lab automation, SDMS, robotics, non-clinical/tox/biology data lakes. Partner with Sr Directors of GXP and Discovery on LIMS program.
• Lead change management efforts for major platform upgrades and new technology rollouts within Discovery, including communication planning, user enablement, and stakeholder alignment.
• Facilitate training sessions, knowledge sharing, and onboarding workshops to increase user adoption and maximize ROI on new Discovery IT investments.
• Oversee technology support activities for key research systems. Ensure Tier 1 through 3 ticket management and execution managing MSP support teams.
• As the IT Business Partner for Discovery, create stories for eLNB or business process-based data (reagent, inventory, laboratory) capture and management by gathering requirements and interactions with Wave Discovery Business Users. Work with the SONAR Product Manager to prioritize stories and SONAR development team to clarify the technical vision of stories for the ultimate delivery of product to the User.
• Partners with Scrum and Kanban teams to coordinate roadmap development, initiatives and continuous system improvements.
• Issue monthly compliance, progress, and operational reports; ensure follow up and escalation as appropriate.
• Lead or co-lead cross-functional Discovery/IT initiatives such as scientific workflow digitization, FAIR data implementation, or research capacity scaling.
• Maintain awareness of state-of-the-art Discovery Informatics activities, industry trends, problem solving techniques and computing practices.
• Coordinate software upgrades with key vendors and managed service partners
• Identify opportunities for Wave to further leverage data to improve its economic, competitive, and operational positioning.
• Establish controls for ensuring efficient and effective data gathering from our scientific experiments and assays.
• Advocate for and champion a data-driven culture, supporting related competencies and data literacy across IT and Wave.

Key Skills

• The individual should be able to function in an agile, dynamic environment, and be able to rapidly adapt to new technologies.
• Prior experience with cloud-based technologies, AWS preferred; experience with analytics and pipelining technologies preferred.
• Prior IT experience in Pharma/Biotech lab and/or manufacturing would be beneficial.

Pay Range External Disclosure Statement

The annual base salary range for this position is $127,000 - $172,000.

The range provided is based on what we believe is a reasonable estimate for the annual base salary pay range for this position at the time of posting. Actual annual base salary will vary based on several factors including, but not limited to, relevant skills, experience, qualifications, position criticality, and internal equity. This position is eligible for a discretionary annual bonus and discretionary stock-based long-term incentives. In addition to compensation, Wave offers a comprehensive and competitive range of benefits designed to support our employees’ and their families physical and financial health and overall well-being. These include, but are not limited to, company-sponsored medical, dental, vision, life, long and short-term disability insurances, generous paid time off (including a week-long company shutdown in the Summer and the Winter), 401K participation with matching contributions, and Employee Stock Purchase Program.

Wave Life Sciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, Wave Life Sciences complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Wave Life Sciences expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status. Improper interference with the ability of Wave Life Sciences’ employees to perform their job duties may result in discipline up to and including discharge.

We value our relationships with professional recruitment firms. To protect the interests of all parties, and given the large volume of inquiries received from third-party placement agencies, we are not able to respond to all agency inquiries. We do not accept unsolicited resumes from any source other than directly from candidates for current or future positions. Submission of unsolicited resumes in advance of a signed agreement between our company and a placement agency does not create an implied obligation and, if an unsolicited candidate represented by a placement agency is hired, we are not obligated to pay a fee. Only approved recruitment firms will be allowed to provide services to Wave Life Sciences, USA.