AstraZeneca

Scientist, Theranostics and Radiation Science

AstraZeneca  •  $93k - $139k/yr  •  Waltham, MA (Hybrid)  •  15 days ago
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Job Description

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generationradioconjugates(RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes but is not limited to: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR cMETtargetedradioconjugatecurrently in a Phase 1 trial.

Fusion has multiple other pipeline programs that will soon be entering into early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliantstate-of-the-artradioconjugatemanufacturing facility to meet supply demand for our growing pipeline of RCs.

Candidates for the Scientist,Theranosticsrole need to work on a hybrid basis out of our Boston, Massachusetts office.

Responsibilities

  • Assistin the development of, and adherence to, imaging trial documents (e.g., Image Review Charter, Imaging Manual, Data Transmittal Forms, and Dosimetry Manuals). 

  • Provide subject matterexpertiseto internal and external stakeholders in matters of image acquisition, storage, review, and processing. 

  • Maintain an archive of imaging related data for ongoing and completed trials. 

  • Collaborate with clinical operations in the oversight, conduct and management of imaging-related aspects of clinical studiesin accordance withthe clinical protocol, study manuals and plans, and timelines while ensuring qualityin accordance withGCP and ICH guidelines. 

  • Assistwith the management of in-house processing of image data and internal dosimetry efforts to support ongoing research and multi-disciplinary department and company initiatives. 

  • Provide support for clinical data review;assistin generation of clinical research reports and presentations including abstracts, posters, and publications. 

  • Provide support to clinical site staff and investigatorspertaining topreparation, administration, and waste management of imaging and therapeutic radiopharmaceuticals.

  • Respond to radiation safety questions and concernsregardingthe use of diagnostic and therapeutic radiopharmaceuticals and precautions. 

  • Have a working knowledge and understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACS, IHE models, imageprocessingand advanced visualization. 

  • Willingness to travel when needed (5-10%)

Qualifications

  • The candidate should have a Bachelor of Science degree with a life science focus from an accredited educational institution and NMTCB/ARRT(N) certification in nuclear medicine or equivalent.Additionaltraining in radiation safety (NMTCB(RS)) and/or medical physics withan advancedmaster's qualifications is preferred but notrequired

  • Minimum of at least 5 years of clinical experience.

  • Experience working in clinical trials for 2-5 years is preferred but notrequired

  • Demonstrated technical and analytical problem-solving skills.

  • Scientificexpertisein SPECT and PET imaging is recommended, including acquisition,reconstructionand uploading of images. 

  • Training in Good Clinical Practices (GCP), Quality Assurance/Compliance (QA/QC) in a clinical trial setting is preferred. 

  • Experience with radioactive materials license amendment process with the NRC and Agreement States. 

  • Familiar with Radiation Safety Officer (RSO) responsibilities. 

  • Ability to clearly articulate and present the role and impact of molecular imaging on decision making within drug discovery and development. 

  • Self-motivation and exceptional verbal and written communication skills. 

  • Ability to multi-task and work effectively in a team or independently on assigned tasks. 

  • Proficiencyin business computer skills and experience with medical imaging workstations 

  •  (i.e., MIM), dosimetry software, and/or PACS preferred.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

The annual base pay for this position ranges from $92,908.00 to $139,362.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coveragein accordance withthe terms of the applicable plans.

Date Posted

12-May-2026

Closing Date

30-May-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca

About AstraZeneca

We're transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet. For more information, visit www.astrazeneca.com.

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Industry
Chemicals & Materials
Company Size
10,000+ employees
Headquarters
Cambridge, GB
Year Founded
Unknown
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