Job Description

The role

This is an exciting opportunity for an experienced scientist to join the Pixelgen R&D team in developing the next generation of groundbreaking single-cell products. We are looking for a hands-on scientist to join our R&D team and take real ownership of the assays behind our next generation of single-cell products, from the first feasibility experiment through to a kit in a customer's hands. We are hiring at either Scientist or Senior Scientist level, depending on experience. This position is set up as a one-year fixed-term contract with a high likelihood of conversion to a permanent full-time position based on performance and business needs.

Responsibilities

• Work within our R&D team to drive the development, optimization, and validation of innovative single-cell product solutions.
• Independently design and execute experiments to understand reaction mechanisms and interactions, process variability, and failure modes.
• Design and build sequencing libraries, and use NGS readouts as the primary measurement for assay performance.
• Maintain and prepare cell lines and other sample material as assay input, and develop the sample-handling steps around them.
• Collaborate cross-functionally with teams in R&D, Computational Biology, and Manufacturing to accelerate product development.
• Analyse experimental data, draw conclusions about assay performance, and translate them into protocol and process improvements.
• Present technical findings/conclusions and project status updates to internal partners.
• Stay up to date with scientific literature and technological advancements across both academia and industry.

Qualifications

• Ph.D or M.Sc with at least 5 years additional experience, in biotechnology, molecular biology, genomics or related field.
• Proven track record in assay or method development of life-science products, ideally in single-cell RNA-seq or single-cell proteomics.
• Hands-on experience with next-generation sequencing and library preparation, including the ability to interpret quality metrics and troubleshoot underperforming libraries.
• Practical cell culture experience: routine maintenance of mammalian cell lines and preparation of cells for downstream molecular workflows.
• Excellent communication and presentation skills, with the ability to effectively communicate scientific information to a diverse range of audiences.
• Ability to work independently and as a part of a cross-functional team.
• Experience with in situ hybridization and padlock-probe assays is preferred but not required.
• Experience with data analysis using python or R is preferred but not required.