Job Description

About the Department

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington and Waltham reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

As part of the establishment of our R&D Hub in greater Boston, Novo Nordisk is growing its efforts within Chemical Biology. We are co-located with target discovery and early drug research groups. As part of a team of leading scientists and innovators, you will bring your own ideas and collaborate with others to develop the next generation of medicines. The working environment in Therapeutics Discovery is dynamic and innovative and involves interactions with colleagues from research sites in Denmark, UK, and China, with an excellent opportunity to establish a strong global scientific network. It’s ground-breaking work with the promise of improving the lives of millions of people with chronic diseases. If you want to make a difference, join us in pioneering research that can achieve a global impact.

The Position

In your role as an LCMS Bioanalytical Scientist II, you will be a part of a team focused on design, development, and execution of novel quantitative liquid chromatographic and mass spectroscopic (LCMS) assays in support of in-vivo and in-vitro pharmacology studies. You will work with diverse modalities, including proteins, peptides, small molecules, oligonucleotides, and their conjugates. You will contribute to understanding PK/PD and biomarkers of interest that drive efficacy and toxicity. You will take part in maturing and advancing scientific ideas within different therapeutic areas through experimental design and execution, ensuring data integrity and reproducibility, and communicating results to diverse project teams. In your daily work, you will collaborate closely with scientists within the Chemical Biology, In-vivo Pharmacology, and other teams across our growing US R&D Hub, and global organization, as well as external CROs and other stakeholders.

This position will provide impactful contributions to project teams by bringing subject and technical matter expertise. It will require excellent critical and detailed analytical evaluations of data that are most relevant to project goals and the effective communication of those evaluations. Importantly this position is predominantly hands on laboratory work building analytical methods, summarizing and interpreting experimental results, and maintaining the instrumentation, reagents, etc.

Relationships

Reports to of the head of the Bioanalysis Department.

Internal relationships include project teams and research colleagues within greater Boston R&D Hub as well as in Denmark and around the globe. Communicates data externally when required. Individual Contributor: does not manage other employees or contingent workers.

Essential Functions

• Impactful contributing team member bringing subject matter and technical expertise:
• Advances research projects by applying knowledge of early drug discovery
• Provides bioanalytical expertise in LCMS systems and its application in, i.e. qualitative and quantitative analysis, PK assays, Met ID, biomarker exploration
• Serves as bioanalytical representative to project teams
• Designs and performs LCMS analytical methods that are fit for purpose and produce quality, value-adding data
• Works with CROs as needed to accomplish analytical work through the establishment of contracts, communication of clear statements of work, and critical oversight of the data produced
• Critical thinking and analytical skills:
• Critically evaluates experimental results, analyzes data using appropriate mathematical modelling and software to create clear written and oral summaries for presentation to project teams
• Independently draws conclusions from experiments and provides input on future directions
• Effective communicator:
• Effectively communicates experimental results within and outside the functional area, guides project teams and other focus groups with subject matter expertise and interpretation, presents and reports to project governance bodies and other stakeholders
• Elucidates with project team how to best interrogate endpoints of interest in alignment with study goals
• Contributes to the dept. team’s knowledge by providing updates on relevant scientific literature and technology
• Laboratory oversight:
• Maintains and troubleshoots relevant lab instruments
• Contributes to effective management of consumables, reagents, sample inventories, and other shared resources

Qualifications

• Bachelor 's Degree required. BS/BA Degree with 8+ years’ relevant experience required, or a master’s degree with 6+ years’ relevant experience, or a Doctoral/PhD degree with 2+ years of relevant experience required

• Relevant experience includes:
• Demonstrated subject matter expertise in LCMS assay concepts, techniques, and technology platforms
• Experienced in analyte extraction and sample preparation from complex biological matrixes for injection onto LCMS systems i.e. protein precipitation, SPE, LLE, IP-MS, etc.
• Work with diverse modalities i.e. antibodies, proteins, peptides, small molecules, oligonucleotides
• Solid understanding of PK/PD modelling concepts as they relate to preclinical animal models and analytical methods
• Practical skills in one or more LCMS systems, methods, and associated software, i.e. Thermo Scientific, Sciex, Waters/Acquity, triple quad, HRMS, column chromatography, Xcalibur, Chromeleon, BioPharma Finder, Proteome Discoverer, Sciex OS, etc.
• Experience working in bioanalytical laboratory
• Preferred experience includes:
• Lab automation and liquid handling instrumentation
• Experience using WinNonlin
• Experience working at or with CROs
• Knowledge of GLP bioanalytical principles
• Demonstrates excellent verbal and written communication skills
• Demonstrates outstanding project management knowledge, as well as organizational and time management skills

The base compensation range for this position is $99,600 to $184,200. Base compensation is determined based on a number of factors. This position is also eligible for a company bonus based on individual and company performance.  

Novo Nordisk offers long-term incentive compensation and or company vehicles depending on the position's level or other company factors.  

 
Employees are also eligible to participate in Company employee benefit programs including medical, dental and vision coverage; life insurance; disability insurance; 401(k) savings plan; flexible spending accounts; employee assistance program; tuition reimbursement program; and voluntary benefits such as group legal, critical illness, identity theft protection, pet insurance and auto/home insurance. The Company also offers time off pursuant to its sick time policy, flex-able vacation policy, and parental leave policy. 

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk, we're not chasing quick fixes – we're creating lasting change for long-term health. For over 100 years, we've been driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and defeating diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger – a legacy of impact that reaches far beyond today.

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.