Job Description

JR151400 Scientist II

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

The Role

• The Scientist II position is part of the method development group in the LC-MS/MS department within the bioanalytical laboratory and plays a key role in the design, development, and optimization of bioanalytical methods. In this role, you will independently develop and refine analytical assays, applying scientific expertise to solve complex method development challenges and ensure robust, fit-for-purpose methods.
• You will work closely with cross-functional teams, including Analysts, Project Managers, and clients, to support the successful execution of method development and validation activities. The role requires a strong balance between hands-on scientific work, data interpretation, and technical troubleshooting, as well as the ability to communicate scientific findings clearly and effectively.
• As an experienced scientist, you will contribute to improving scientific approaches and mentor junior team members. You are expected to work with a high degree of independence while ensuring all activities are conducted in compliance with GxP and internal quality standards.

Responsibilities

• Develop and optimize LC‑MS methods to analyze a variety of compounds in biological samples such as plasma, urine, and tissues
• Contribute to method development and validation projects, helping to troubleshoot issues and ensure high-quality results
• Support Project Managers by providing technical input and assisting with troubleshooting during study execution (including validation activities in line with ICH M10 expectations)
• Work closely with cross-functional teams, including laboratory, operational, and clinical colleagues
• Communicate effectively with clients to discuss progress, challenges, and solutions during development and validation work

Minimum Qualification Requirements

• Bachelor’s degree in a scientific field with 5–7 years of relevant industry experience
• Master’s degree in a scientific field with 3–5 years of relevant industry experience
• Ph.D. in Analytical or Bioanalytical Chemistry with 1–3 years of relevant experience

Additional Preferences

• Experience working in an industry setting, with strong organizational skills and attention to detail
• Hands-on experience with LC‑MS systems (triple quadrupole required; familiarity with high-resolution systems is a plus)
• Experience with sample preparation techniques such as protein precipitation, solid phase extraction, and immunoprecipitation
• Familiarity with bioanalytical workflows for peptides, proteins, or oligonucleotides
• Experience or interest in metabolic profiling is preferred
• Familiarity with laboratory systems and tools such as LIMS, Watson, Analyst, or comparable platforms
• Strong problem-solving mindset and willingness to take initiative
• Proficient in written and spoken English
• Basic knowledge of Dutch is considered an advantage

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What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements

• A range of health insurance offerings to suit you and your family’s needs.

• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.

• Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being.

• Life assurance

• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply