Champions Oncology, Inc.

Scientist I, Radiopharmacology

Champions Oncology, Inc.  •  $82k - $96k/yr  •  Rockville, MD (Onsite)  •  3 months ago
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Job Description

Level: Experienced
Job Location: Rockville MD - Rockville, MD 20850
Position Type: Full TimeEducation
Level: PhD
Salary Range: $82,000.00 - $96,000.00 Salary/year
Travel Percentage: None
Job Shift: Day
Job Category: ResearchPOSITION TITLE: Scientist I, Radiopharmacology
REPORTING LOCATION: Rockville, MD
REPORTS TO: Head of Radiopharmacology
PRIMARY OBJECTIVE: Join our team to advance radiochemistry and cancer research, supporting the launch of our in vivo radio conjugate program. Support the operations and commercial teams for in vivo study planning and execution utilizing radio conjugates for testing in Champions extensive PDX Tumorbank in preclinical mouse pharmacology studies.
DUTIES, RESPONSIBILITIES AND PRODUCTIVITY EXPECTATIONS:
- Design and execute radiolabeling reactions using a range of isotopes, including Lu-177, Ac-225, In-111, Zr-89, At-211, I-131, and Pb-212.
- Perform conjugation reactions between bifunctional chelators and peptides or proteins.
- Develop and optimize radiochemical synthesis protocols for both diagnostic and therapeutic applications.
- Conduct quality control and stability testing of radiolabeled
- Analyze experimental data, interpret results, and communicate findings to cross-functional teams.
- Support preclinical research studies, including biodistribution, pharmacokinetics, and dosimetry assessments.
- Prepare, review, and ensure compliance of study protocols and technical reports
- Train and mentor junior staff in radiochemistry techniques, radiation safety, and handling of radioactive materials.
- Maintain accurate laboratory records
- Stay current with advancements in radiochemistry, nuclear medicine, and isotope production technologies.
- Assist in the evaluation and implementation of new equipment, automation systems, and analytical tools.
- Perform additional duties as assigned verbally at any time.

QualificationsKNOWLEDGE, SKILLS, AND ABILITIES:
- Expertise in radiochemistry, radiobiology, molecular imaging, and therapeutic radionuclide production and handling.
- Expertise in chromatography techniques such as thin-layer chromatography (TLC), column chromatography, high-performance liquid chromatography (HPLC).
- Expertise in conducting in vivo studies using radiolabeled compounds
- Experience with analysis and interpretation in vivo data of radioconjugate pharmaceuticals.
EDUCATION AND EXPERIENCE:
- PhD in a relevant field (e.g., radiochemistry, chemistry, biochemistry, pharmaceutical sciences).
- Expertise in radiochemistry, radiobiology, molecular imaging, and therapeutic radionuclide production.
- Experience with analysis and interpretation in vivo data of radioconjugates.
- Strong computer, organizational, and multitasking skills.
- Excellent communication skills.
PHYSICAL DEMANDS AND WORK ENVIRONMENT:
- Must be able to sit and use hands to finger, handle and feel.
- Must be able to lift and move packages weighing up to 50 pounds.
- Must be able to sit for long periods of time using a computer in a typical office environment in a multi-level facility.
- Some activities require repetitive motion and reaching, pulling, or pushing.
- In carrying out the duties of the job there will be frequent exposure to fumes and chemical hazards
- Duties performed routinely require exposure to blood, body fluid, and tissue.
This description reflects management’s assignment of essential functions, it does not proscribe or restrict the tasks that may be assigned.  We celebrate diversity and are committed to creating an inclusive environment for all employees.
Champions Oncology, Inc.

About Champions Oncology, Inc.

Champions Oncology, Inc. provides an end-to-end range of research and development solutions and services that improve the productivity of oncology drug development. Using both in vitro to in vivo testing platforms companies can leverage the expertise at Champions Oncology to help guide decision making for clinical development scenarios.

From screens using commercially-available and custom cell lines, to studies leveraging syngeneic or traditional patient-derived studies xenograft (PDX) models, and modeling treatment response in the clinic, Champions Oncology is your partner in meeting today’s needs and innovating for tomorrow’s challenges.

At the core of our services is the Champions TumorGraft® (CTG) platform, a comprehensive, unique compendium of PDX models that preserve the biological characteristics of human tumors and are highly predictive of clinical outcomes. Services utilizing Champions TumorGrafts® PDX tumor models include evaluating tumor sensitivity/resistance to various single, combination, standard and novel chemotherapy agents, biomarker discovery and the identification of novel drug combinations.

Champions TumorGraft® PDX models are procured through agreements our Clinical Collaboration Network, a series of renowned oncology institutions in the US and around the world, as well as through the company’s Personalized Oncology Solutions business.

Personalized Oncology Solutions assist clinical oncologists by establishing and administering expert tumor panels for their patients to analyze medical records and test results, to assist in understanding conventional and experimental options and to identify and arrange for testing, analysis and study of the patients’ cancer tissues, as appropriate. Additionally, the company offers personalized PDX development, drug studies and genome sequencing, whereby physicians evaluate the effects of cancer drugs and understand the genetic makeup of each patient’s tumor, enabling them to better select treatment regimens.

Industry
Unknown
Company Size
51-200 employees
Headquarters
Hackensack, New Jersey
Year Founded
2007
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