Job Title: Scientist, Drug Product Development
Location: Toulouse
Department: Process & Product Design
Reports To: Senior Manager, Drug Product Development
We’re excited to share this opportunity is part of the Sandoz acquisition of Just-Evotec Biologics in Toulouse. Through this opportunity you will impact the lives of hundreds of millions of people through bold ideas supported by an inclusive, agile company culture. Join us to help make healthcare fairer and faster, help us to pioneer access to medicine!Click to learn more.
What You’ll Do:
·Design and execute phase-appropriate formulation, drug product process development and stability studies.
Implement pharmaceutical product development strategy and conduct formulation development and PD process experiments.
Represent the Drug Product Development function and work collaboratively with cross-functional P&PD teams to achieve organizational goals
Work with external CMOs for outsourced activities, including pharmaceutical manufacturing.
Execute development strategies to increase efficiency and reduce risk of FIH, NIF and commercial formulations.
Optimize development strategies for biosimilar formulations, considering intellectual property challenges.
Act as a team member and collaborate with Just organization partner groups, including analytical, quality control, quality assurance and manufacturing teams, to ensure product quality and stability.
Act as an internal technical resource for Quality, Manufacturing and Process Design, as well as a resource and subject matter expert for external clients and collaborators
Be a technical resource to internal and external teams regarding formulation, stability and container closure for designing drug product
Who You Are:
Holder of a Master’s degree in biotechnology, bioprocess engineering, pharmaceutical sciences, biochemistry or related filed with 0 to 5 years of relevant experience
Knowledgeable and experienced with Biologics/Protein/peptide formulation and DP process development (mandatory)
Able to prove practical hands-on experience of analytical techniques including HPLC/UPLC, Capillary Electrophoresis (CE), Isoelectric Focussing (IEF), Sub-visible particle analysis/characterization, DLS, DSC etc.
Knowledgeable on design experiments (DoE) tools such as JMP, MODDE etc. and statistical analysis for biologic and/or biosimilar products.
Comfortable with deep understanding of protein degradation and stabilization mechanisms
Experienced in Drug product development and/or manufacturing of sterile injectable dosage forms including frozen, liquid, formulations in vials, pre-filled syringes and autoinjectors (will be preferred).
Knowledgeable of regulatory guidance from the FDA and EMA for development of biologic drug products and biosimilars
Knowledgeable of USP and Ph. Eur. as it relates to biologics development
Language : very comfortable in English, including the ability to communicate effectively over teleconference and web-based meetings. At ease in French would be an added advantage
Dynamic, having good interpersonal skills and being a team player
Having a comprehensive written and verbal French communication skills will be an added advantage
Why Sandoz?
Generic and Biosimilar medicines are the backbone of the global medicines industry. Sandoz, a leader in this sector, provided more than 900 million patient treatments across 100+ countries in 2024 and while we are proud of this achievement, we have an ambition to do more!
With investments in new development capabilities, state-of-the-art production sites, new acquisitions, and partnerships, we have the opportunity to shape the future of Sandoz and help more patients gain access to low-cost, high-quality medicines, sustainably.
Our momentum and entrepreneurial spirit is powered by an open, collaborative culture driven by our talented and ambitious colleagues, who, in return for applying their skills experience an agile and collegiate environment with impactful, flexible-hybrid careers, where diversity is welcomed and where personal growth is encouraged!
The future is ours to shape!
FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.
ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.
Evotec is a biotechnology company that is committed to advancing drug discovery and development. Through flexible business models, we collaborate with pharmaceutical companies, biotechs, foundations, and government agencies on a substantial scale. We believe that by working together, we can make a difference in the lives of patients.
Our Pipeline Co-Creation model represents our adaptable, multi-modality, fully integrated end-to-end approach to drive collaborations and services across all phases of drug discovery and development – from discovery of novel targets to achieving Proof of Concept in the clinic and into commercial manufacturing.
We aspire to contribute data-driven disease understanding and early disease relevance in humans to bring the probability of success up. We select the right modality, which is then propelled forward on our platforms by our passionate people striving for the fastest and most effective ways towards patient impact. This is enabled by convergence of human ingenuity with data and AI.
We also offer specific solutions, products, and CRO/CDMO-like services, always in support of the Biopharma R&D innovator. Our more than 4,000 scientists work closely with numerous partners concurrently, delivering fully integrated research and development portfolios or individual projects with the highest quality standards and efficiency, coupled with great science, passion, engagement, and communication.
