Job Description

Cambridge, US; Gaithersburg, US; New Jersey, US | full time | Job ID: 11654

About the Role:

As a Clinical Pharmacology and Pharmacometrics Scientist, you’ll turn pharmacokinetic, pharmacodynamic and modeling data into decisions that advance BioNTech’s drug development pipeline. Your work will help teams understand drug candidates, select doses and develop new treatments for patients. You’ll work across clinical research, translational sciences, biomarker operations and research. Together, you’ll design studies, interpret results and support development strategies and regulatory submissions.

Your contribution:

• Lead the analysis, interpretation and reporting of clinical pharmacokinetic data to inform development decisions
• Drive pharmacokinetic and pharmacodynamic, exposure-response and translational modeling to build mechanistic understanding and guide dose and dosing schedules
• Plan, design and oversee program-specific clinical pharmacology studies, including QT, food-effect, ADME, drug–drug interaction and special-population assessments
• Partner with research leads to design and interpret pharmacokinetic, toxicokinetic and pharmacodynamic aspects of preclinical studies
• Collaborate with cross-functional teams and provide timely scientific input for internal and regulatory interactions
• Contribute to clinical pharmacology and pharmacometrics sections of regulatory documents, such as investigator brochures, briefing books and marketing applications

A good match:

• A Ph.D. in pharmaceutics, pharmacokinetics, pharmacology, pharmacometrics or a related discipline with experience in clinical pharmacology, drug development, translational research or pharmacometrics, including PK/PD, exposure-response or translational modeling
• A strong understanding of pharmacokinetic and pharmacodynamic data in the context of complex biology; experience in oncology, infectious diseases or another relevant therapeutic area is an advantage
• Proficiency with pharmacokinetic and modeling software such as Phoenix WinNonlin, R, NONMEM or MATLAB
• Clear scientific communication, strong organizational skills and thorough documentation
• Ability to work independently, take initiative and collaborate with multidisciplinary teams, along with proficiency in written and spoken English

Join us at BioNTech where your expertise will contribute directly to improving patient outcomes worldwide. Together we can shape the future of medicine.

Your benefits and remuneration:

Expected Pay Range: $99,100/year to $158,700/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
• 401(K) Plan with Company Match
• Tuition Reimbursement & Student Loan Assistance Programs
• Wellbeing Incentive Platforms & Incentives
• Professional Development Programs
• Commuting Allowance and subsidized parking
• Discounted Home, Auto & Pet Insurance

…and more! More details to be shared.

Home to dozens of research institutions, biopharmaceutical companies, life science incubators, venture capital firms, and over 30 million square feet of laboratory space, Cambridge, Massachusetts has earned a reputation as the #1 life science cluster in the world. As part of the Greater Boston area, the city is often referred to as the "biotech supercluster" due to its high concentration of life sciences firms. This unique ecosystem is the result of a model partnership between academia and industry, fostering collaboration and innovation and driving the development of new therapies, medical devices, and diagnostics. As Cambridge’s thriving life sciences industry continues to evolve, the city remains a beacon of knowledge, innovation, and collaboration, poised to shape the future of science and technology.

Apply now - We look forward to your application!

Apply for our Cambridge, US; Gaithersburg, US; New Jersey, US location and simply send us your documents using our online form.

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.