Job Description

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.
We are seeking a motivated and independently driven Scientist to join our team investigating Parkinson’s disease biology using iPSC-derived cells and in vivo models. The successful candidate will oversee animal studies and data analysis, and design and execute cell-based assays to advance our understanding of Parkinson’s disease within a collaborative, cross-functional research team.

Key Responsibilities:

• Design, optimize, and perform cell-based assays using iPSC-derived cells
• Conduct standard molecular biology experiments including Western blot, ELISA, flow cytometry, etc.
• Perform cell-based imaging and immunohistochemistry (IHC) to assess protein localization, expression, and cellular phenotypes
• Manage external collaborations and coordinate activities with contract research organizations (CROs)
• Analyze, interpret, and present experimental data to project teams and external partners
• Collaborate effectively with scientists across multiple therapeutic areas and functional groups
• Maintain detailed experimental records and contribute to scientific reports and publications

Required Qualifications:

• PhD in Immunology, Neuroscience, or related field
• Demonstrated expertise in mammalian cell culture techniques
• Proficiency in standard molecular biology methods
• Experience with imaging techniques
• Strong analytical and problem-solving skills
• Excellent written and verbal communication skills
• Proven ability to work both independently and collaboratively in team settings
• Strong organizational skills and attention to detail

Preferred Qualifications:

• Hands-on experience with iPSC culture and differentiation
• Experience with immunohistochemistry (IHC)
• Experience managing CRO relationships or external collaborations
• Track record of scientific presentations and/or publications

#LI-DM1
At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.  
Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us!  We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.  
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation. 
Review our Privacy Policy