Genentech

Scientist 3, Immunology and Ophthalmology, Sudharsan Lab

Genentech  •  $103k - $192k/yr  •  South San Francisco, CA (Onsite)  •  2 hours ago
Apply
AI can make mistakes so check important info. Chat history is never stored.

Job Description

The Opportunity

The Sudharsan Lab in the Department of Immunology and Ophthalmology at Genentech is seeking a highly motivated, resilient, and curious Scientist 3 to drive the target identification, validation, and development of novel therapies for retinal diseases, with a strong focus on Age-Related Macular Degeneration (AMD).

As part of Genentech Research and Early Development (gRED), scientists bridge basic biology and translational drug discovery. In this role, you will design and execute research strategies using advanced retinal cellular systems to validate targets, elucidate disease mechanisms, and advance novel therapies. You will collaborate closely with multidisciplinary teams to translate biological insights into therapeutic candidates and share your findings at internal forums and external conferences.

Key Responsibilities

  • Develop human iPSC-derived retinal models (such as RPE and photoreceptors) and design cell-based assays to validate novel targets, study AMD pathogenesis, and evaluate therapeutic candidates.
  • Quickly learn and implement new experimental workflows and analytical tools as project priorities evolve.
  • Maintain rigorous experimental design, meticulous electronic lab records, and high standards of data reproducibility.
  • Collaborate effectively with interdisciplinary teams across the department and broader gRED functional areas.
  • Communicate research findings clearly across internal project teams and at external scientific conferences.

Who You Are

  • Ph.D. in Stem Cell Biology, Neuroscience, Cell Biology, Developmental Biology, Ophthalmology, or a closely related scientific discipline.
  • Strong background in cell culture-based assay development, execution, and troubleshooting.
  • Experience with human induced pluripotent stem cell (iPSC) culture, maintenance, and differentiation workflows.
  • A strong track record of peer-reviewed publications in reputable scientific journals.
  • Excellent interpersonal and collaborative skills with a proven ability to work effectively within large, cross-functional group settings.
  • A strong desire and enthusiasm to learn and integrate new experimental techniques, assays, and analytical tools.

Preferred:

  • Direct research experience in retinal cell biology, ocular tissue models, or specialized research in Age-Related Macular Degeneration (AMD) or inherited retinal degenerations.
  • Experience with gene editing approaches and/or omics technologies (e.g., single-cell RNA-seq, spatial transcriptomics, or proteomics).
  • Experience with 3D retinal organoids, multi-cell co-culture systems, or advanced tissue engineering platforms.
  • Familiarity with target engagement assays, high-throughput screening, or translational pipeline workflows.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $103,400 to $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Genentech

About Genentech

About Genentech

We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal.

Making a difference in the lives of millions starts when you make a change in yours. If you’d like to join our team, view our openings at gene.com/careers.

Our patient resource center is dedicated to getting patients and caregivers to the right resources. You can reach them at 1 (877) GENENTECH (436-3683)

Monday-Friday, 6am-5pm PST or patientinfo@gene.com.

Community Guidelines:

1. We want to foster positive conversation around the issues we are passionate about. To that end, we remove profanity, content that contains threatening language, content that is aimed at private individuals, personal information, and repeated unwanted messages.

2. Don’t mention any medicines by name — ours or anyone else’s.

Because of the fair balance rules governing our industry, we cannot post any comments that reference any pharmaceutical brand, product, or service. Please do not mention any specific medicines by name, or include any links to third party sites in your comments.

3. This isn’t the place to report or discuss side effects.

This site is not intended as a forum for reporting side effects experienced while taking a Genentech product. Instead, you should report any side effects to Genentech Drug Safety at 1-888-835-2555. You can also report side effects of any prescription product directly to the FDA at 1-800-FDA-1088 or by visiting www.FDA.gov/medwatch.

4. Don’t pitch your product or service.

Please don't use our page as a place to promote your product or pitch your services. Please also avoid posting links to external sites. We reserve the right to remove any posts that are deemed promotional.

Industry
Biotech & Life Sciences
Company Size
10,000+ employees
Headquarters
South San Francisco, California
Year Founded
1976
Website
gene.com
Social Media