The Nathan P. Staff Laboratory is seeking a highly motivated Postdoctoral Fellow to investigate the cellular and molecular mechanisms of amyotrophic lateral sclerosis (ALS) using iPSC‑derived motor neuron models from patients with genetic forms of ALS. The fellow will design and execute experiments that combine advanced stem‑cell culture and differentiation, CRISPR‑based perturbations, high‑content imaging, electrophysiology, and transcriptomic/proteomic analyses to dissect pathways in axonal transport, RNA/protein homeostasis, and to identify and validate therapeutic targets. Responsibilities include quantitative data analysis, manuscript preparation, presentation of findings at national meetings, and collaborative work with clinicians, bioengineers, and computational scientists.
A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.
Must have a Ph.D., M.D., or equivalent doctoral degree in neuroscience, cell biology, bioengineering, genetics, or related field.
Hands‑on expertise with human iPSC culture/differentiation strongly preferred.
Proficiency in one or more of CRISPR editing, electrophysiology, quantitative imaging, or -omics; and a strong publication record.
The ability to work as a team player within and outside of the program.
We offer a collaborative, well‑resourced environment with access to state‑of‑the‑art core facilities, competitive salary/benefits, and individualized career development.
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
Mayo Clinic has expanded and changed in many ways, but our values remain true to the vision of our founders. Our primary value – The needs of the patient come first – guides our plans and decisions as we create the future of health care. Join us and you'll find a culture of teamwork, professionalism and mutual respect, and most importantly, a life-changing career.
Mayo Clinic was founded in Rochester, Minnesota by brothers Dr. William James Mayo and Dr. Charles Horace Mayo. More than 100 years later, their vision continues to evolve around a single guiding value: "The needs of the patient come first." Today we are the largest integrated, not for-profit medical group practice in the world.
We are recognized for high-quality patient care more than any other academic medical center in the nation. These endorsements are very gratifying, but also humbling. They remind us of the tradition that has been entrusted to each one of us, and the legacy of excellence that we uphold every day.
