We are seeking a motivated and technically skilled intern (PhD level) to support research and development activities in downstream processing of extracellular vesicles (EVs) and viral vectors. The successful candidate will work closely with a multidisciplinary team to optimize and execute purification workflows using tangential flow filtration (TFF) and chromatography-based methods. This internship provides hands-on experience in biologics processing and analytical evaluation, contributing directly to process development for therapeutic nanoparticles.
Hands on position starting September 2025 for a minimum of six months up to a maximum of ten months
Onsite at our Marlborough, MA site,
In the Research Intern role, you will serve as a critical contributor to the development and integration of Sartorius’ emerging technologies for characterization and purification of different types of nanoparticles such as extracellular vesicles and viral vectors. These leading-edge platforms will be utilized in basic research as well as the pharmaceutical and biotechnology industries.
What you will accomplish together with us
Execute Purification Protocols Perform purification of EVs and viral vectors using TFF systems (hollow fiber and/or flat sheet) and various chromatography modalities (e.g., ion exchange, size exclusion, affinity).
Optimize Unit Operations Assist in the design and optimization of downstream steps to improve product yield, purity, and scalability
System Operation and Maintenance Operate and maintain TFF and chromatography systems (e.g., AKTA or equivalent), including set-up, cleaning, and troubleshooting.
Sample Handling and Quantification Prepare and process samples following SOPs. Quantify particles using orthogonal methods such as NTA, qPCR, protein assays, and total RNA analysis.
Process Monitoring and Data Recording Monitor and document key parameters (e.g., transmembrane pressure, flux, recovery) during TFF runs. Maintain detailed lab notebooks and process logs.
Analytical Support Support integration of downstream data with analytical assays (e.g., flow cytometry, SEC-MALS, SDS-PAGE) for process characterization.
Collaborative Work Interact regularly with upstream, analytical, and formulation teams to align on process goals and transfer knowledge.
Safety and Compliance Follow laboratory safety protocols and ensure compliance with quality standards and experimental reproducibility.
What will convince us
Education:
Experience:
Hands-on experience with TFF systems (lab or pilot scale) for nanoparticle or biologics concentration and diafiltration.
Practical knowledge of chromatography techniques such as SEC, IEX, or affinity purification.
Familiarity with nanoparticle systems such as EVs, viral vectors (e.g., AAV, lentivirus), or LNPs.
Comfortable working in a wet lab environment with complex biological samples.
Strong documentation and organizational skills; experience with SOPs and batch records is a plus.
Experience with analytical tools (e.g., NTA, BCA, qPCR, HPLC, or SEC-MALS) is highly desirable
Compensation is up to $30 hr.
What We Offer
As a growing global life science company, with our stock listed on the German DAX and TecDAX , Sartorius offers a wide range of benefits:
Personal and Professional Development: Mentoring, leadership programs, internal seminar offerings
Making an Impact Right from the Start: Comprehensive onboarding, including a virtual online platform
Welcoming Culture: Mutual support, team spirit and international collaboration; communities on numerous topics such as “Coaching”, “Agile Working” and a “Businesswomen’s Network”
Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.
Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, disability or based on status in any other protected group of class.
Please view equal employment opportunity posters provided by OFCCP here.
Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment. Join our global team and become part of the solution. We are looking forward to receiving your application.
We look forward to receiving your application.
If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at accommodationrequest@sartorius.com
Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, or disability, or based on status in any other protected group of class.
If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at accommodationrequest@sartorius.com
About Sartorius
Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide.
We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.
Join our global team and become part of the solution. We are looking forward to receiving your application.
www.sartorius.com/careers
Sartorius is a leading international partner of life sciences research and biopharmaceutical manufacturing.
We help our customers simplify progress from drug discovery to manufacturing so that more people can have access to better medicine. With this, we are part of the solution in the fight against diseases worldwide.
With innovative laboratory instruments and consumables, the Lab Products & Services division focuses on laboratories performing research and quality control at pharmaceutical and biopharmaceutical companies as well as academic research institutes.
The Bioprocess Solutions division, with its broad product portfolio focusing on single-use solutions, helps customers manufacture biotech medications, vaccines, and cell and gene therapies safely, rapidly, and economically.
Based in Göttingen, Germany, Sartorius also has a strong global reach with more than 60 production and sales sites worldwide. We regularly expand our portfolio through the acquisition of complementary technologies.
In 2024, Sartorius generated sales revenue of around 3.4 billion euros. Currently, more than 13,500 employees from around 110 nations are working for customers around the globe.
Join our team, partner or collaborate with us.
