The Gut Microbiome Laboratory, housed within the Enteric Neurosciences Program at Mayo Clinic (Rochester, MN), is seeking a highly motivated, self-driven postdoctoral fellow to join a collaborative and translational research team focused on defining pathophysiological mechanisms underlying gastrointestinal motility disorders.
Our program represents one of the largest and most integrated groups of physicians and scientists studying the enteric nervous system and gastrointestinal physiology, with a long history of paradigm-shifting discoveries that have shaped the field. We are seeking new team members who are excited to contribute to, and extend, this distinguished tradition.
The laboratory is at the forefront of research in human neurogastrointestinal disorders, including irritable bowel syndrome (IBS). We employ an integrated experimental approach that combines physiology, advanced imaging, molecular and cellular biology, and in vivo animal models to interrogate gut-microbe-host interactions. Our work is published in high-impact journals (Gastroenterology, Cell, Cell Host & Microbe, and Science Translational Medicine) and is supported by NIH funding.
We provide extensive resources, mentorship, and a highly collaborative environment to support trainees as they advance to the next stages of their careers. We are committed to fostering a diverse, inclusive, and supportive culture, and we value community, celebrating milestones together, and creating space to recognize both scientific accomplishments and the people behind them.
Qualified candidates should hold a PhD or MD/PhD in physiology, neuroscience, molecular biology, or a related discipline and be within five years of PhD completion. This position is not intended for clinical training and is not open to MD/MBBS candidates seeking clinical roles.
Experience in advanced imaging, single-cell or spatial transcriptomics, and mouse physiological studies is highly desirable, and candidates with expertise in these areas are strongly encouraged to apply.
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights

Mayo Clinic has expanded and changed in many ways, but our values remain true to the vision of our founders. Our primary value – The needs of the patient come first – guides our plans and decisions as we create the future of health care. Join us and you'll find a culture of teamwork, professionalism and mutual respect, and most importantly, a life-changing career.
Mayo Clinic was founded in Rochester, Minnesota by brothers Dr. William James Mayo and Dr. Charles Horace Mayo. More than 100 years later, their vision continues to evolve around a single guiding value: "The needs of the patient come first." Today we are the largest integrated, not for-profit medical group practice in the world.
We are recognized for high-quality patient care more than any other academic medical center in the nation. These endorsements are very gratifying, but also humbling. They remind us of the tradition that has been entrusted to each one of us, and the legacy of excellence that we uphold every day.