Job Description

ABOUT US

At Quell we seek to discover, develop, and deliver pioneering Treg therapies to durably transform the lives of people suffering from immune-mediated diseases. Our vision as a company is to build a major global biopharmaceutical company bringing transformational and valued therapies for a range of autoimmune and inflammatory diseases.

OUR COMPANY

Quell is a London‑based clinical‑stage biotechnology company developing engineered regulatory T cell (Treg) therapies for immune‑mediated diseases. Its lead asset, QEL‑005, is a pipeline‑in‑a‑product for complex autoimmune diseases and is being evaluated in the Phase 1/2 CHILL clinical trial. Founded in 2019 with leading immunology experts from King’s College London, University College London and Hannover Medical School, Quell is backed by investors including Syncona, SV Health Investors, Jeito Capital, Ridgeback Capital and Fidelity.

THE ROLE

Research Associate – Technical Development

We are looking to recruit a Research Associate to expand our Technical Development team. The team is working very closely with Research and Development department and will contribute to creation of best ways of manufacturing process to help to develop our CAR-Treg therapies and will be involved in generating next generation products.

The individual will be working very closely with R&D, internal and external manufacturing teams while participating in the effective running of daily operations process development team and will contribute to creation of best ways of manufacturing process to help to develop our CAR-Treg therapies.

This position offers an excellent opportunity for a talented and motivated technician to contribute to a key part of our work. Quell offers an exciting and highly dynamic environment focused on developing cutting-edge Treg therapies.

The role requires being onsite 5 days per week and will require flexibility to travel between both London sites (White City and London Bridge)

MAIN RESPONSIBILITIES

• Conduct experiments under supervision
• Manage databases and assist in establishing relevant SOPs.
• Contribute to improvement of existing process design, regarding efficiency and quality
• Assist in designing, conducting, optimizing, and evaluating new processes in manufacture within GMP environment
• To ensure that all studies, tests and procedures performed in the laboratory follow quality procedures.
• Handle mammalian and primary human immune cell cultures and performing cell culturing, cell isolation, cryopreservation and other processing techniques.
• Use various methodologies including flow cytometry, FACS, ELISA.
• Perform analytical assays and transfer the process to manufacturing team.
• Ensure all processes and documentation comply with the required standard.
• To take responsibility for cleanroom and support day to day lab operations.
• Collaborate and coordinate work with other teammates to meet deadlines and goals

ESSENTIAL SKILLS AND EXPERIENCE

• Understanding of immunology and cell therapy.
• Primary human immune cell cultures in an aseptic manner.
• Demonstrable expertise in cell-based techniques including magnetic enrichment basic flow cytometry.
• Ability to overcome challenges and possess the ability to thrive in a fast-paced environment.
• Excellent time management and prioritising skills.
• Minimum BSc degree in a relevant study field
• Proven commitment to high quality work and maintenance of high standards.
• Contribute to a culture that embraces scientific excellence, integrity, urgency, patient centricity and continuous improvement.

PERSONAL QUALITIES

• Ability to work collaboratively within a team, supporting one another and held accountable for project deliverables.
• Detail-orientated and highly accurate.
• Professional and personable communication skills.
• Driven to solve problems pragmatically.
• Demonstrates strong organisational and prioritisation skills to manage a diverse workload.
• Good working attitude, reliability, and flexibility.
• Desire to work with integrity and act as an ambassador for Quell and the wider business.

BENEFITS

• Holidays: 25 days per year.
• Life Assurance: 4 x base salary.
• Group Personal Pension: Auto enrolled at 6% employer contribution, 3% employee contribution.
• Private Medical Insurance for your whole family.
• Annual Bonus.

PERKS

• Fantastic collaborative environment at Translation & Innovation Hub
  • Click here for Virtual Tour
• Brand new lab equipment, innovative methods, and exposure to cutting edge technology.
• Fast paced and progressive company looking for future leaders and innovators.