The purpose of the In Vivo Research Associate II/III position is to independently conduct in vivo studies in support of the Company's goals and objectives.
Responsibilities:
- Works closely with Study Directors, Study Coordinators and cross functional team members to ensure all assigned studies are conducted in accordance with study protocols, standard operating procedures and company policies
- Collection of body weight data
- Collection of tumor volume measurements
- Collect tissue samples and process for shipment to sponsor as well as internal purposes
- Responsible for the tracking of samples and shipping of samples to sponsor companies
- Preparation of animals for procedures, including shaving, ear tagging and other tasks as directed
- Performance of clinical observations and humane euthanasia in mice
- Collect relevant data and provide feedback to team members regarding progress of assigned projects
- Perform advanced in vivo procedures (including sample collection, surgeries.) with minimal direct supervision required
- May be trained on more complex procedures
- Perform subcutaneous inoculations
- Administer therapeutic agents through different routes of administration, including IP, PO, SC, IM, ID, IN and IV
- Providing general group support by cleaning, general supply stocking and sample shipping
- Responsible for tracking time spent on projects (project logs)
Minimum Requirements:
- Bachelor's degree is required
- 2-3 years of experience handling animals in a Vivarium environment is required
- Comfortable working in a laboratory animal research environment
- Demonstrated ability to perform a minimum of three of the following in vivo oncology tumor models in mice:
- Animal handling
- Tumor implantation
- Tumor measurement
- Gross necropsy
- Simple drug preparation
- Drug administration by various routes
- Minor survival surgery
- In-life and terminal bleeds
- Demonstrated sense of integrity and confidentiality
- Planning, organizational skills and flexibility in a reactive environment
- Demonstrated accountability and responsibility for own work
- Ability to follow standard operating procedures, observe safety and security procedures
- Able to troubleshoot effectively and solve problems with supervision
Preferred Requirements:
- AALAS certification at ALAT level or higher is preferred
Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.
Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) dedicated to accelerating drug discovery and development in oncology and immuno-oncology. We partner with biotech and pharmaceutical companies to provide innovative, tailored solutions spanning preclinical research, translational platforms, and clinical trial support.
With the world’s largest commercially available patient-derived xenograft (PDX) collection and approximately 1,000 tumor organoid models powered by Hubrecht Organoid Technology, we offer unparalleled insights across 35 cancer indications.
Our expertise spans in vivo, in vitro, ex vivo, and in silico methods, complemented by advanced laboratory services that span the entire drug development continuum. Additionally, our extensive biobank of liquid and human biospecimens, complete with clinical histories, enhances oncology research capabilities.
Operating from 11 state-of-the-art facilities across the US, Europe, and APAC, our laboratories meet the highest industry standards, including accreditation by the College of American Pathologists (CAP) and the International Organization for Standardization (ISO).
To learn more, visit www.crownbio.com.
