Crown Bioscience

Research Associate I, In Vivo

Crown Bioscience  •  United States (Onsite)  •  3 months ago
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Job Description

The Research Associate (RA) at Crown Bioscience North Carolina will support the execution of in vivo research studies, contributing to the advancement of oncology and pharmacology research. The RA will work closely with scientists and senior research staff to carry out experiments, maintain animal models, collect and analyze data, and assist in the development of novel research techniques. This position plays a critical role in ensuring the quality and integrity of preclinical studies.

Responsibilities:

· Assist study director/scientist and senior research associates (SRA) in the design and execution of research studies, including protocol and IACUC documentation.

· Develop, maintain, and manage xenograft models, including patient-derived xenografts (PDX), in rodent models.

· Perform in vivo procedures such as tumor cells inoculation/tumor fragment transplantation, tumor measurement, compound dosing (oral, IP, IV, etc.), and biological sample collection (blood, tissue, etc.), etc.

· Collect, organize, and interpret experimental data using standard data analysis software and methodologies.

· Contribute to the preparation of reports, summaries, and presentations of research findings.

· Collaborate with team members across departments and participate in internal/external project meetings to support study execution.

· Maintain precise and organized documentation of experimental procedures and results in lab records and study files.

· Ensure adherence to animal welfare regulations, research protocols, and laboratory best practices.

· Complete additional assignments or tasks as delegated by supervisors.

Minimum Requirements:

· Bachelor's degree in biology, pharmacology, physiology, animal science, or a related field.

· Strong analytical, observational, and problem-solving skills.

· Familiarity with in vivo research techniques and experience working with animal models.

· Proficiency in data collection and basic data analysis tools (e.g., Excel, GraphPad Prism).

· Excellent verbal and written communication skills.

· Ability to work independently and collaboratively in a fast-paced, team-oriented environment.

Preferred Requirements:

· Master’s degree in biology or pharmacology is preferred.

· Prior hands-on experience with rodent models, including surgical procedures, dosing, and sample collection.

· Experience working with patient-derived xenograft (PDX) models is strongly preferred.

· Familiarity with regulatory guidelines, including IACUC protocols and animal welfare standards.

· Experience contributing to peer-reviewed publications or scientific presentations is a plus.

Crown Bioscience is committed to a diverse and inclusive workplace. Crown Bioscience is an equal opportunity employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

Crown Bioscience

About Crown Bioscience

Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) dedicated to accelerating drug discovery and development in oncology and immuno-oncology. We partner with biotech and pharmaceutical companies to provide innovative, tailored solutions spanning preclinical research, translational platforms, and clinical trial support.

With the world’s largest commercially available patient-derived xenograft (PDX) collection and approximately 1,000 tumor organoid models powered by Hubrecht Organoid Technology, we offer unparalleled insights across 35 cancer indications.

Our expertise spans in vivo, in vitro, ex vivo, and in silico methods, complemented by advanced laboratory services that span the entire drug development continuum. Additionally, our extensive biobank of liquid and human biospecimens, complete with clinical histories, enhances oncology research capabilities.

Operating from 11 state-of-the-art facilities across the US, Europe, and APAC, our laboratories meet the highest industry standards, including accreditation by the College of American Pathologists (CAP) and the International Organization for Standardization (ISO).

To learn more, visit www.crownbio.com.

Industry
Biotech & Life Sciences
Company Size
501-1,000 employees
Headquarters
San Diego, California
Year Founded
Unknown
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