Job Description

Monte Rosa Therapeutics is seeking a contractor (6 months) with the experience to implement and run complex cellular assays. This position is a key role in the pivotal team responsible for Automation and Screening Technologies & hits-to-leads support for Monte Rosa’s diverse pipeline. The ideal candidate will be able to help evolve Monte Rosa’s hit identification and hits-to-leads endeavors through embracing novel assay technologies, enhancing overall processes and actively drive internal and external partnerships.

Responsibilities

• Perform a variety of molecular and cellular biology techniques, including CRISPR knock-in, mammalian cell culture, DNA/RNA isolation, and Western blotting, functional readouts in specific cell types (e.g. cytokine measurement).
• Implement and help to execute cell-based assays using various technologies (e.g., fluorescence, luminescence, TR-FRET, AlphaScreen)
• Utilize automated liquid handling systems and laboratory robotics
• Analyze and interpret experimental data, compile results, and present findings to the team
• Maintain cell lines and prepare stock solutions
• Manage laboratory inventories and handle biohazardous materials according to safety protocols
• Ensure compliance with laboratory safety procedures and guidelines

Qualifications

• Minimum bachelor’s degree or equivalent in Biochemistry, Cell Biology or life science with at least 2-4 years of industrial experience.
• Experience in High Throughput Screenings and Cellular assays for compound profiling is essential.
• Experience with mammalian cell culture and cell line generation is preferred.
• Knowledge of Genedata software package is preferred.
• Proven track record for striving for high level of innovation and scientific excellence.
• Flexibility to accommodate rapidly changing priorities and deadlines.
• Ability to work in a team-based environment.
• Excellent oral and written communication skills.