Job Description

Salary: £36,636 to £38,784 per annum (pro rata)

Newcastle University is a great place to work, with excellent benefits We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

Closing Date: 21 July 2026

The Role

Join the John Walton Muscular Dystrophy Research Centre, a world-leading translational research team dedicated to improving the lives of people with genetic neuromuscular diseases. Working alongside a multidisciplinary team of clinicians, scientists, and bioinformaticians, you will analyse cutting-edge omics datasets, including single nuclei RNA sequencing and spatial transcriptomics, to uncover disease mechanisms, identify biomarkers and support the development of new diagnostics and therapies.

This is an exciting opportunity to apply and expand your bioinformatics expertise in a highly collaborative, clinically embedded research environment, contributing directly to research with real patient impact.

The position is particularly suited to candidates seeking to build a strong track record in translational omics within a clinically embedded research setting.

The project focuses on the analysis of large-scale omics datasets, including single nuclei RNA sequencing and spatial transcriptomics, generated from muscle biopsies and related biological samples from patients with muscular dystrophies. Through integrative and high-dimensional data analysis, the aim is to uncover novel disease mechanisms, identify biomarkers, and support the development of improved diagnostic and therapeutic strategies.

You will play a central role in extracting biological insight from these complex datasets, contributing to ongoing efforts to better understand disease progression and variability in neuromuscular disorders.

This post is fixed term for a period of 8 months. This is a part time role (7.4 hours per week).

For informal enquiries contact: Prof Giorgio Tasca ( giorgio.tasca@newcastle.ac.uk).

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/

Find out more about our Research Institutes here:

https://www.ncl.ac.uk/medical-sciences/research/institutes/

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

Key Accountabilities

• Support a range of research activities across the JWMDRC, besides the specified project
• Provide guidance on ongoing and future research, particularly experimental design, omics data analysis and interpretation
• Keep up to date with new developments in the bioinformatics field and apply them to the diverse range of data generated within the JWMDRC lab
• Collect, analyse and interpret research data and draw conclusions on the outcomes
• Co-ordinate own work with that of others, use problem solving to affect the achievement of research objectives and contribute to the planning of the project(s)
• Present information on research progress and outcomes to a Principal Investigator or groups overseeing the research project
• Write up results from own research activity and provide input into the research project’s dissemination, in whatever form (report, papers, chapters, books)
• Use research resources (including, where required, laboratories, workshops and specialist equipment) as appropriate
• Contribute ideas, including enhancements to the technical or methodological aspects of the project
• Determine appropriate methodologies for research
• Assess research findings for the need/scope for further investigations
• Contribute to the writing up of the research and its dissemination, either through seminar and conference presentations or through publications
• Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
• Contribute to grant applications submitted by others and develop own research objectives and proposals for funding

The Person

Knowledge, Skills and Experience

• Hands-on experience in the analysis of large-scale omics data, including complex multistage pipeline development, reporting, and troubleshooting
• Proficiency in programming (e.g. using Linux/Python and R), command-line applications, and programming standards such as version control
• Understanding of the application of statistical methods to omics studies
• Attention to detail and ability to work at high levels of accuracy
• Ability to present complex information effectively to a range of audiences
• Proven ability to analyse data and write-up results
• Experience of working collaboratively with colleagues
• Excellent IT skills in all major office applications
• The ability to use personal initiative and creativity to solve research problems.
• Awareness of the research environment
• High level of analytical and problem solving capacity
• Ability to communicate complex information with clarity
• Experience of presentations at conferences and/or in high quality publications

Desirable

• Experience with single cell/single nuclei RNA sequencing and/or spatial transcriptomics datasets
• Subject knowledge in muscle biology and pathophysiology of muscle diseases
• Experience in working with human tissue samples

Attributes and Behaviour

• Enthusiastic, hardworking and able to take initiative
• Ability to work independently and as part of a team
• Capability to develop new skills
• Good time management and ability to prioritise to meet deadlines
• Commitment to working positively as a member of a multi-skilled research team
• Ability to negotiate and prioritise multiple, competing responsibilities and to work to deadlines
• Commitment to continued professional development
• Understanding of good practice in equality, inclusion and diversity

Qualifications

• A PhD in the research area required

Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.

We are committed to being a fully inclusive university which actively recruits, supports and retains colleagues from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all of our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from individuals who can complement our existing teams, we believe that success is built on having teams whose backgrounds and experiences reflect the diversity of our university and student population.

At Newcastle University we hold a Gold Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC. We are a Disability Confident employer and will offer an interview to disabled applicants who meet the essential criteria for the role as part of the offer and interview scheme.

In addition, we are a member of the Euraxess initiative supporting researchers in Europe.

Requisition ID: 29540