
and Responsibilities
The James/Guthridge Lab ( james.omrf.org; guthridge.omrf.org) is hiring a Research Assistant Professor (transitional faculty member) to assist with analysis of large, complex, multi-modal datasets from clinical trials and clinical research protocols. The successful candidate will have training and expertise in computational biology, systems immunology, bioinformatics, biostatistics, machine learning, or related quantitative disciplines to add to one of the nation's leading multidisciplinary autoimmune disease research programs, OMRF Arthritis & Clinical Immunology
This position offers an exceptional opportunity to become part of a highly collaborative team of physician-scientists, immunologists, computational biologists, geneticists, epidemiologists, and data scientists dedicated to understanding the mechanisms underlying autoimmune diseases and developing strategies to predict, prevent, and treat them.
The successful candidate will leverage large, deeply phenotyped, multi-modal datasets generated from patients with autoimmune diseases and individuals at risk for developing autoimmunity. Available data include high-dimensional molecular, cellular, genetic, genomic, transcriptomic, proteomic, metabolomic, clinical, imaging, and longitudinal biospecimen datasets derived from peripheral blood and disease-relevant tissues. These resources provide outstanding opportunities for integrative analyses, biomarker discovery, mechanistic investigation, disease prediction, and precision medicine.
This is a transitional position for scientists who have completed a graduate degree and an exemplary postdoctoral experience who have been evaluated as being likely to develop high-caliber independent or collaborative projects and to attract extramural grant support. Successful candidates are characterized by considerable experience, highly distinctive competence, and a demonstrated ability to perform both independently and as a critical member of a large multi-disciplinary productive team.
Minimum Qualifications
Preferred Qualifications
OMRF Overview
Founded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation’s oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer’s disease, cancer, lupus, multiple sclerosis, and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nation’s leaders in patents per scientist.
Located in Oklahoma City, a city that offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy, OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a collective commitment to our mission, “. . . so that more may live longer, healthier lives.” Successful candidates will demonstrate commitment to this mission.
OMRF Benefits
We offer competitive salaries and comprehensive benefits to full-time employees including medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, and paid holidays. All employees have access to our onsite café, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro. Learn more about our benefits here
OMRF is an Equal Opportunity Employer.

Established in 1946, OMRF is an independent, nonprofit biomedical research institute with more than 450 staff and over 50 labs studying cancer, heart disease, autoimmune disorders, and diseases of aging.
Breakthroughs in our labs have led to three FDA-approved drugs, including the first targeted therapy approved in the U.S. for sickle cell disease and the first approved treatment for neuromyelitis optica spectrum disorder, a rare autoimmune disease. OMRF’s critical research is helping people live longer, healthier lives, one discovery at a time.
Along the way, OMRF has garnered worldwide media attention, from leading scientific publications like The New England Journal of Medicine and Science to The New York Times and The Wall Street Journal. By pushing the boundaries of biomedical science, our researchers are helping to win the war against human disease, one discovery at a time.