
Join the team behind one of the largest and most advanced imaging centers in North America; where every day brings variety, collaboration, and purpose. As a Non-Vascular Radiology Diagnostic Nurse at Mayo Clinic in Rochester, you’ll be part of a fast-paced, high-acuity environment supporting 15 imaging locations, including a dedicated pediatric practice and caring for 1,400–1,600 patients daily across all ages and acuity levels.
Our nurses provide diagnostic support across modalities including CT, MRI, ultrasound, and nuclear medicine. They perform rapid assessments, start IVs, access ports, and respond to urgent needs such as strokes and Level 1 Trauma emergencies. You’ll work alongside technologists, radiologists, and nursing peers in a highly autonomous environment, guided by evidence-based practice and grounded in teamwork.
Why Choose Mayo Clinic’s Non-Vascular Radiology Diagnostic Team?
• Largest Imaging Center in North America: Support a broad spectrum of patients across 15 imaging sites, including a dedicated pediatric practice, with 47 MRI and 32 CT scanners in Rochester.
• Dynamic, Autonomous Practice: Thrive in a fast-paced environment that blends independence, critical thinking, and collaboration.
• High-Impact Clinical Experience: Provide essential diagnostic support and respond to complex, time-sensitive patient needs.
• Cutting-Edge Technology: Work with advanced imaging equipment in an expanding practice that continues to evolve and grow.
• Research & Quality Innovation: Partner with the Radiology Quality Office and dedicated research teams to advance care, improve processes, and shape the future of radiology nursing.
• Supportive Team Culture: Experience low turnover, strong peer collaboration, and the assurance that you’re never working alone.
• Balanced Work Environment: Enjoy minimal call expectations, flexible scheduling, and a strong focus on work-life balance.
• Career Growth & Benefits: Access Mayo Clinic’s Nurse Residency and Career Investment Programs, comprehensive benefits, and continuing education to support your long-term professional development.
• Purpose-Driven Culture: Join a mission-focused organization that combines innovation, compassion, and excellence in patient care.
Join us in reimagining the future of healthcare. At Mayo Clinic in Rochester, Minnesota, we're building the care model of tomorrow, powered by innovation and driven by purpose. As a registered nurse here, you’ll be part of a collaborative, high-acuity environment where evidence-based practice and compassion go hand in hand. This is where your calling meets world-changing care.
For New Graduate Nurses: Please apply through the Nurse Residency Program posting, which is specifically designed to support new graduate RNs. Visit the Nurse Residency webpage for program details including current and upcoming application windows. Within the Nurse Residency application process, you may indicate work units and specialties of interest. If selected to move forward, you will meet with a Nursing Placement Coordinator who will help you explore Mayo Clinic opportunities that are best aligned with your current and future professional goals. Together, we’ll identify a work area that provides an excellent foundation for your nursing career.
The registered nurse (RN) is accountable for the coordination of nursing care, including direct patient care, patient/family education and transitions of care. The RN supports professional nursing practice across practice settings and across the continuum of care to meet the needs of the patient and family. The RN will function within the Mayo Clinic Nursing Professional Practice Model, which includes accountability for planning, implementing, evaluating and communicating all phases of nursing care for assigned patients. The ANA Nursing: Scope and Standards of Practice provide a basis for the practice of the RN. The RN provides leadership through activities such as preceptor role, informal and formal leadership roles, and quality improvement efforts. The RN delegates patient care according to skill level, experience, patient acuity, fiscal accountability and availability of resources. The RN possesses excellent communication skills; is skillful in mentoring and teaching; and may participate on committees or projects. A subset of employees may be required to drive their personal vehicle as a part of the responsibility of their role.
This role is eligible for TN sponsorship. Holders of F1 status eligible for post-completion OPT are welcome to apply. This role is NOT eligible to participate in the F-1 STEM OPT extension program. Successful sponsorship will require state licensure and completion of the VisaScreen or equivalent certification.
Ability to wear lead and to push, pull, and lift up to 50 pounds is required.
Ability to work with arms above shoulder level, and repetitive movement with hands and wrists above shoulder level is required.
ACLS/ECG required within first 6-9 months of start date.
Excellent communication skills (verbal and written).
Experience working in a team environment.
Computer skills required, prior experience with electronic medical record systems preferred.
Ability to work flexible hours. Ability to adapt to unpredictable situations within the work setting.
Applicants with implants/devices, such as a pacemaker or defibrillator (ICD), are putting themselves at risk.
Demonstrated leadership, effective communicator, and excellent critical thinking skills.
Additional specialty certification/training as required by the work area.
Internal applicants should attach their three most recent performance appraisals.
License and Certifications:
Current RN license by applicable state requirements.
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights

Mayo Clinic has expanded and changed in many ways, but our values remain true to the vision of our founders. Our primary value – The needs of the patient come first – guides our plans and decisions as we create the future of health care. Join us and you'll find a culture of teamwork, professionalism and mutual respect, and most importantly, a life-changing career.
Mayo Clinic was founded in Rochester, Minnesota by brothers Dr. William James Mayo and Dr. Charles Horace Mayo. More than 100 years later, their vision continues to evolve around a single guiding value: "The needs of the patient come first." Today we are the largest integrated, not for-profit medical group practice in the world.
We are recognized for high-quality patient care more than any other academic medical center in the nation. These endorsements are very gratifying, but also humbling. They remind us of the tradition that has been entrusted to each one of us, and the legacy of excellence that we uphold every day.