Job Description

About us

Chiesi is an international research-focused biopharmaceutical group with 90 years’ experience, operating in more than 30 countries, with its Headquarter in Parma, Italy. More than 8,000 employees across the group are united by a singular purpose: promoting a healthier world for our people, patients, and the planet. This is what drives us as we research, develop, and market innovative drugs across our main therapeutic areas. Discover more here.

At Chiesi we are thinking generations ahead, driving sustainable innovation with purpose. This fosters a culture of reliability, transparency, and ethical behaviour at every level. As a Benefit Corporation and a certified B Corp, we have embedded sustainability in our bylaws and continuously measure our impact.

Diversity and inclusion are at the heart of who we are. We believe our differences make us stronger. We are a vibrant ecosystem of passionate, talented individuals united by strong values, each bringing unique perspectives that help us to continuously challenge the status quo for the better.

Chiesi Global Rare Diseases

Chiesi Global Rare Diseases is a Chiesi Group’s business unit established in February 2020 and focused on research, development and commercialization of treatments and patient support services for rare and ultra-rare disorders, many of whom have limited or no treatments available.

This unit is based in Boston, Massachusetts, with a strong synergy with the headquarters in Parma.

Rare unit has a focus on research and product development for lysosomal storage diseases, rare hematology, ophthalmology disorders and rare immunodeficiencies. The unit is also a dedicated partner with global leaders in scientific research, patient advocacy and care. Discover more here

What we are looking for

This is what you will do

Within the Global Rare Diseases Global Medical Affairs, reporting to the Head of Real World Evidence, the Real World Evidence Lead is responsible for shaping and executing the organisation’s RWE vision. This position focuses on building and improving RWE capabilities, establishing robust processes, and driving impactful evidence generation in collaboration with internal and external partners. The role emphasises strategic planning, change management, and oversight of studies conducted through CROs.

You will be responsible for

• Strategic Leadership & IEGP – Lead development and implementation of RWE strategies and methodologies aligned with Integrated Evidence Generation Planning across our HIDO portfolio – Hematology, Dermatology, Immunology & Ophthalmology
• RWE Start-Up & Capability Building – Establish and continuously improve RWE capabilities, processes, and infrastructure to support global and local evidence generation. Act as a change agent, effectively communicating the value of RWE and influencing adoption of new processes and approaches
• Study Oversight with CROs – Provide strategic oversight for design, initiation, and execution of RWE studies managed by CROs, ensuring quality and compliance
• Concept Reviews – Lead and participate in concept reviews for proposed RWE studies, ensuring alignment with scientific and business objectives

You will need to have

• Advanced degree (e.g., MSc, PhD, PharmD, DrPH, MD) in epidemiology, public health, health economics, or related field. A clinical background should be supplemented with advanced quantitative training in data science, biomedical informatics, health informatics, clinical informatics, epidemiology, biostatistics, health economics and outcomes research, engineering or a related field required.
• Significant experience in RWE, observational research, or related disciplines within the pharmaceutical/biotech industry or CRO environment.
• Demonstrated ability to lead and execute RWE projects and manage external partners with minimal, or no, supervision using real-world data from claims, electronic health records, registries, biobanks, and/or digital applications.
• Proven track record in establishing or improving RWE capabilities and processes.
• Strong change management and influencing skills, with experience driving adoption of new approaches.
• Excellent conceptual, integrative, and communication skills; able to translate complex evidence into actionable insights for diverse audiences.
• Stakeholders/cross-functional engagement: works effectively across functions and geographies to deliver integrated evidence generation; experience in presenting RWE to Medical Affairs or cross-functional colleagues, as well as a science/clinical audience; ensures high-quality execution of RWE studies through CRO oversight.

Technical/Methodological Skills

• Proficiency in epidemiological study design (cohort, case-control, cross-sectional etc)
• Experience with causal inference methods (propensity score matching etc)
• Familiarity with database claims, EHR, patient registries
• Ability to develop and implement long-term RWE strategies aligned with organisational goals.
• Ability to critically appraise external RWE publications and vendor proposals/protocols
• Regulatory/scientific infrastructure: Familiarity with FDA and EMA guidance on RWD, RWE and related topics.
• Tools & analytics: Experience with data governance and privacy regulations (HIPAA, GPRD etc)

We would prefer for you to have

Experience in rare diseases or similar therapeutic areas is an advantage.

Location

The role can be based in one of Chiesi affiliates in Europe with an estimated 20% travel requirement, including international travel.

What we offer

No matter where your path starts at Chiesi, it leads to inspiring possibilities. Your future is our focus, and we are committed to nurturing your development in our dynamic, friendly environment with access to resources and training every step of the way.

We provide top-class benefits, including comprehensive healthcare programs, work-life balance initiatives, and robust relocation support. Our salary package is competitive, comprising a basic salary, performance bonuses, and benefits benchmarked against the external market. Additionally, we offer flexible working arrangements, remote work options, and tax assistance services for foreign colleagues, all designed to help you thrive.

Chiesi is an equal opportunity employer committed to hiring a diverse workforce at all levels of our business. All qualified applicants receive consideration for employment based on attitude and merit, without regard to race, national origin, age, sex, religion, disability, sexual orientation, marital status, military status, gender identity or expression, or any other basis protected by applicable laws. This policy applies to all aspects of employment, including hiring, transfer, promotion, compensation, eligibility for benefits, and termination.