Job Description

Salary Range:

€27,160.00 - €50,440.00#LI-Hybrid
Location: Menges, Slovenia

Role Purpose:
Our R&D unit in Mengeš is looking for a motivated scientist in field of formulation development to join our unit and help us develop a diverse portfolio of biotherapeutic modalities.
As a Senior Scientist you must demonstrate a broad and in-depth knowledge of pre-formulation/formulation and characterization to evaluate the developability of various biologics modalities covered by Novartis Biomedical Research and Development units, ranging from traditional antibodies to advanced biologics formats and mixed modalities. You will help shape the overall formulation strategy for large biomolecules before the project transition from research into early phase development and help funnel out unfavorable candidates with respect to formulation assessment.
We offer a stimulating work environment, ample opportunities for growth and development, and the chance to make a significant impact on the future of medicine. If you are a motivated and talented scientist with a passion for biomedical research, we invite you to apply and become a part of our dynamic team at Novartis.

Naša R&D enota v Mengšu išče motiviranega raziskovalca s področja razvoja formulacij, ki bi se pridružil naši enoti in nam pomagal razvijati raznolik portfelj bioterapevtikov.

Kot Raziskovalec ekspert morate izkazovati široko in poglobljeno znanje s področja predformulacij/formulacij in karakterizacije za ocenjevanje razvojne primernosti različnih bioloških modalitet, ki jih pokrivajo enote Novartis Biomedicinske raziskave in Razvoj, od tradicionalnih protiteles do naprednih bioloških formatov in mešanih modalitet. Pomagali boste oblikovati celovito strategijo formulacije za velike biomolekule pred prehodom projekta iz raziskovalne faze v zgodnjo fazo razvoja ter prispevali k izločanju neugodnih kandidatov glede na oceno formulacije.

Nudimo spodbudno delovno okolje, številne priložnosti za rast in razvoj ter možnost pomembnega vpliva na prihodnost medicine. Če ste motiviran in nadarjen raziskovalec s strastjo do biomedicinskih raziskav, vas vabimo, da se prijavite in postanete del naše dinamične ekipe v Novartisu.

Key Responsibilities:

• Perform pre-formulation assessment for large biotherapeutics focusing on recombinant monoclonal antibodies, multispecific antibodies and other therapeutic proteins, including but not limited to solubility assessment,
• Set-up of formulation screening studies, performing biophysical characterization methods such as DSC/DSF, dynamic light scattering (DLS), UV-Vis, turbidity, sub visible particle assessment, viscosity and other techniques that are LC based method (SEC, HIC) for characterizing therapeutic proteins.
• Lead screening experiments to identify stable formulations, and collaborate results and designs independently to research and development organizations
• Utilize state-of-the-art liquid handlers for compounding of formulations for large biotherapeutics to conduct stability studies on them
• Conduct physico-chemical analytics methods for characterization of various formats of biotherapeutics in screening, pre-formulation development and lead optimization stages
• Operate and maintain instrumentations, perform data analysis and ELN documentation, and author method development and technical reports.
• Work in a highly interdisciplinary and collaborative environment as part of the global BRC team and contribute to data analysis and interpretation, making technical presentations and report writing

Minimum Requirements - What you will bring to the role

• MSc degree in biochemistry, biotechnology, chemistry or a related field with at least 3 year of relevant work experience, or BSc University degree in biochemistry, biotechnology, chemistry or a related field with with at least 6 years of relevant work experience
• Hands-on experience with protein drug delivery and characterization
• Demonstrated technical understanding and expertise in the field of formulation sciences of large biotherapeutic molecules
• Demonstrated expertise with hands-on experience of setting up preformulation assessments and use of different stability indicating assays such as SEC/CE/DLS (including but not limited to) to interpret the formulation studies data
• High learning ability to acquire expertise in new technologies and technical equipment
• Proven experience in successfully prioritizing and keeping timelines
• Open and proactive communication, strong customer focus, ability to interact with various stakeholders
• Reliable and flexible team player, accustomed to sharing tasks and projects
• Fluency in English (oral/written)

Benefits & Rewards

At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.

Expected Annual Base Salary Range for role: € 27,160 to € 50,440

The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.

In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.

The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.

Pričakovani letni osnovni plačni razpon za delovno mesto: €27,160 do € 50,440

Osnovna plača je določena glede na spolno nevtralne cilje, kot so relevantne veščine, kompetence in izkušnje v skladu s politiko plač Novartisa, ob vstopu v Novartis pa se redno pregleduje.

Poleg osnovne plače ste morda upravičeni do bonusa na podlagi uspešnosti, odvisno od določenih parametrov uspešnosti.

Nagrade, ki jih prinaša članstvo v naši ekipi, segajo daleč preko osnovne plače in spodbud. Ponujamo tudi različne konkurenčne ugodnosti v naravi, ki vam pomagajo uspevati osebno in poklicno, kot so zavarovalni načrti, pokojninski načrti, viri za dobro počutje in globalni programi priznanja. Poleg tega ponujamo prilagodljive in hibridne možnosti dela, kjer je mogoče, ter najmanj 14 tednov plačanega starševskega dopusta.

Skills Desired