Job Description

General Summary:

The Project Management Associate Director will operationally lead the integration, creation and execution of multiple complex departmental development plans within Medical Affairs as a member of the Medical Affairs Project Management team. Partnering closely with Project Leaders, Global Medical Leads (GMLs), Regional Medical Leads (RMLs), and cross-functional teams, the incumbent will ensure delivery of strategic and operational priorities across disease areas and geographies. This role requires a proactive, strategic thinker with strong judgment who can manage diverse needs, drive cross‑functional alignment, and ensure seamless execution of Medical Affairs objectives. Responsibilities span project planning, risk and governance management, status reporting, and development of processes, tools, and frameworks that advance departmental effectiveness.

Key Duties and Responsibilities:

• Operationally leads Medical Affairs Integrated Medical Planning (IMP), ensuring alignment of strategic integrated medical plans, budgets, goals, timelines, KPIs, vendor management, and cross‑functional deliverables.
• Facilitates governance reviews (GMAT, cross‑functional workshops, evidence forums), and drives follow‑through of approved initiatives to enable achievement of program and medical objectives.
• Independently leads and manages multiple, complex projects providing operational discipline, scenario planning, and risk mitigation recommendations.
• Develops and harmonizes dashboards, executive communications, and reporting, including EC presentations, insights dashboards, and cross‑functional reports. Proactively provides key project issues and status to senior management to ensure alignment

• Effectively summarizes key information such as program progress, timeline updates, and risk/opportunity assessments for periodic presentations to management

• Compiles succinct reports and prepare minutes for select internal meetings; methodically tracks all action items, and finds new ways to stay abreast of these multi-dimensional tasks

• Maintain frequent communication with the network of cross-functional internal and external stakeholders so that all parties are aware of current program status, issues, contingencies, and milestones

• Coordinates the tools used within the department

Knowledge and Skills:

• Identifies opportunities to improve project management processes, tools, and ways of working; contributes to Medical Affairs Program Management best practices.
• Outstanding communication of information and ideas (written, PowerPoint, verbal), to varied audiences including senior and executive leadership
• Analytical, able to glean insights from data using excel and other tools, and communicate in a compelling, visual way
• Strong collaboration skills, with an ability to influence multiple stakeholders; builds mutual trust, respect and cooperation among team members
• Proven project management skills, including scenario analysis, business acumen and the ability to manage multiple tasks and priorities; adapt to new projects rapidly and effectively
• Strategic thinker with a track record of driving results
• Self-motivated; acts independently and prioritizes appropriately; embraces unexpected changes or challenges and drives to improved solutions in a fast-paced environment
• Proven ability to work in and influence a cross-functional team promoting collaboration and high performing team behaviors with an unwavering focus on what is best for the patients we serve
• Consistently displays sound ethics, good judgment and demonstrates Vertex’s core values
• Strong biopharmaceutical drug discovery and development acumen across multiple disciplines

Education and Experience:

• Requires a Bachelor's degree
• Advanced degree (MBA) or comparable experience strongly preferred
• Typically requires 8 years of work experience, or the equivalent combination of education and experience, in project managementpreferably within Medical Affairs

Pay Range:

$155,700 - $233,500

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid work remotely up to two days per week; or select
2. On-Site work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com