Job Description

Senti Bio is seeking an enthusiastic, self-driven Research Associate to join its Process Development team that is focused on advancing new products and enabling technologies. This role will be part of a team of associates and scientists that develop processes and technologies for manufacturing NK-cell therapies. The position will require experimental execution, troubleshooting and optimization of processes, data analysis, drafting of and presentation of results.

Responsibilites

• Contribute to process development for cell therapy development programs, including natural killer (NK cells) and other therapeutic cell modalities
• Perform small- and large-scale experiments using primary cells to support multiple operations including expansion, gene editing, selection/expansion of clones, cell harvest and cryopreservation
• Perform transductions on primary human cells via viral vectors and other gene delivery methods
• Supports process optimization efforts to increase process robustness, improve transduction efficiency, cell yield and purity
• Contribute to donor screening and testing processes using high-throughput assays.
• Collaborate with research teams on relevant ex-vivo assays (Flow Cytometry, ELISA, Luminex based assays and PCR)
• Maintain accurate lab records and notebooks
• Author protocols, reports and standard operating procedure documents
• Present results in team meetings and delivers presentation to both small and large groups

Qualifications

• Bachelor’s or Master’s degree in Cell & Molecular Biology or related life science field, with a minimum of 2 years of experience, preferably in process development setting
• Experience with mammalian tissue culture including both adherent and suspension cells.
• Proficiency with flow cytometry strongly preferred.
• Ability to design and execute experiments with minimal technical supervision. Ability to multitask and meet deadlines in a fast-paced environment.
• Highly organized and detailed oriented individual with strong troubleshooting and problem-solving skills
• Must be a team player, proactive and willing to work in a small team environment.
• Must have excellent verbal and written communication skills.
• Proficient with MS office and other commonly used software and technology platforms.
• Self-motivated and eager to take on temporary responsibilities outside of initial job description.

Salary and Benefits

• Compensation for this role includes hourly base salary
• The base hourly range for this role is $45-56 per hour. Starting pay is determined by multiple job-related factors including a candidate’s skills, education and experience level, benchmark, and internal parity.
• Significant growth opportunity as the company expands.
• Empathetic, supportive, and collaborative colleagues and work environments