Clario is a global leader with more than five decades of experience advancing clinical trial technology. Our solutions streamline evidence collection, improve data accuracy, and accelerate decision‑making—ultimately helping life‑changing therapies reach patients faster. As a Principal Software Engineer I, you will play a vital role in delivering secure, scalable, and reliable systems that support next‑generation clinical research.
What We Offer
Competitive compensation
Medical, dental, and vision insurance beginning Day 1 of employment
Flexible work schedules
Attractive PTO plan
Engaging employee programs
Remote working
What You’ll Be Doing
Design and develop software application deployments.
Implement full CI/CD pipelines and automate deployment workflows.
Create and run automated testing routines to ensure stable, error‑free deployments.
Support DevOps initiatives by automating manual release and build processes.
Develop and manage infrastructure automation and cloud environments (AWS, Azure).
Train IT and development teams on infrastructure automation best practices.
Monitor and maintain software security, performance, and SLAs.
Provide Tier III support and ensure optimal application functionality.
What We Look For
Bachelor’s degree in Computer Science, Software Engineering, or related field
Minimum of 5+ years of professional software development experience
Proven, hands-on experience with .NET and C# development at a senior or lead level
Strong background in SQL, PL/SQL, and Postgres (backend database focus)
Experience conducting requirement analysis and writing unit test cases
Ability to work in Agile development environments
Exposure to CI/CD tools (e.g., Git, Jenkins) is a plus but not required
Excellent documentation and communication skills
Experience in regulated environments (e.g., pharmaceuticals, healthcare) is a plus
Based in or able to work from the United States (remote/hybrid/on‑site).
At Clario, our purpose is to transform lives by unlocking better evidence. It’s a cause that unites and inspires us. It’s why we come to work—and how we empower our people to make a positive impact every day. Whether you're advancing clinical science, building innovative technology, or supporting our global teams, your work helps bring life‑changing therapies to patients faster.
Clario is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.

Clario is a leading healthcare research and technology company that generates high quality clinical evidence for our pharmaceutical, biotech, and medical device partners. We offer comprehensive evidence generation solutions that combine eCOA, cardiac safety, medical imaging, precision motion, and respiratory endpoints.
Since our founding more than 50 years ago, Clario has delivered deep scientific expertise and broad endpoint technologies to help transform lives around the world. Our endpoint data solutions have supported clinical trials over 26,000 times in more than 100 countries. Our global team of science, technology, and operational experts have supported over 60% of all FDA drug approvals since 2019.
For more information, visit Clario.com