
Principal Scientist:
Lead and manage a multidisciplinary scientific team of 12-15 FTEs ensuring high-quality project delivery.
Handle client communications and independently manage technical calls with global stakeholders.
Oversee project planning, execution, timelines, and resource allocation.
Provide scientific guidance, troubleshooting, and mentoring to team members.
Ensure compliance with quality, safety, and organizational standards.
Collaborate cross-functionally to support business and operational goals.
Organic Chemist:
Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance
Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography
Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations
Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately
Peptide Chemist:
Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM
Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS
Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities
Skilled in laboratory operations, equipment maintenance, SHE compliance, literature review, and accurate experimental documentation
Scaleup Chemist:
Experience in process R&D, scale-up synthesis, and purification from gm to kg scale
Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities
Proficient in 1H NMR, HPLC, and LCMS interpretation
Strong project execution and team collaboration skills
Antibody Drug Conjugation Chemist (ADC)
Synthesis and purification of complex antibody drug conjugate (ADC) molecules
Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs
Synthesis of highly potent drug molecules – payloads
Purification of complex and large molecules by flash column and HPLC
Handling various type chemistry with different payloads
Interpretation and characterisation of higher molecular weight compounds
Principal Scientist;
PhD/MSc in Organic Chemistry / Medicinal Chemistry or related field.
Strong experience in CRO/CDMO research environment.
Proven team management experience with exposure to handling multiple projects.
Excellent communication and client-facing skills.
Ability to drive productivity, scientific excellence, and team development.
Organic Chemist:
Master’s in Organic Chemistry with 1-3 years of experience in the CRO Industry
Strong organisational, project management and problem-solving skills with impeccable multi-tasking abilities.
Proactive, highly motivated with a "can do" attitude
Exceptional interpersonal skills.
Peptide/Scaleup/Antibody Drug Conjugation (ADC) Chemist:
Master’s in Organic Chemistry with a minimum of 2 years and a maximum of 6 years of experience in the CRO/API Industry
Adherence to safe practices and procedures
Contribution to the development of safety protocols and systems
Must be able to prioritize and organize work responsibilities in order to meet deadlines

o2h group seeds new ideas in science, technology and green innovation. We work across boundaries and take a collaborative and shared approach to innovation, and therefore we co-invest, co-create and co-execute to bring these ideas to life. o2h group is organised into 6 symbiotic verticals; o2h ventures, o2h discovery, o2h therapeutics, o2h technology, o2h co-work, and o2h community.
o2h discovery is an integrated chemistry and biology services platform for executing collaborative research. o2h technology works on proprietary software projects for in-house portfolio companies.
o2h ventures is an engine for nurturing early stage life science and technology assets through seed investment.
o2h therapeutics is seeding a novel pipeline of proprietary pre-clinical IP in Immunoncology (glioblastoma, breast cancer), anti-ageing and diabetes.
o2h co-working space located in Hauxton, Cambridge, UK and o2h community covers our work with local non-profits organisations, our interests in working with social enterprise and our work in creating a community of innovators that can impact society.
o2h group is co-located in Ahmedabad, India and in Cambridge UK. Please see www.o2h.com for more details.