
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
Principal Production Engineer — Operations
About Lilly
At Lilly, everything we do starts with patients. We unite caring with discovery to make life better for people around the world. Headquartered in Indianapolis, Indiana, our global team of over 50,000 employees work with urgency and purpose to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. We bring our best to this work because people depend on it. If you’re driven by purpose and determined to make a meaningful difference for patients, we invite you to bring your skill and your commitment to Lilly.
About Tech@Lilly
At Lilly, technology is not a support function. It is how a global medicine company operates, innovates, and delivers. Lilly in Hyderabad builds the capabilities that make this possible, cloud platforms, AI systems, and automation at enterprise scale, all in service of a purpose that makes this technology work genuinely distinctive, from advancing drug discovery to enabling connected clinical trials to keeping a global medicine company running at the standard patients deserve.
Experience
10+ years
Location
Hyderabad (Onsite)
Employment Type
Full-time
Job Family
R3 — Operations / Application Support / Production Engineering / SRE-aligned Support
Time Allocation
Majority operational coverage and incident command · 20–30% engineering and toil reduction
Technology at Lilly builds and operates mission-critical digital products and platforms that support the discovery, development, and delivery of medicines that make life better for people around the world. Our teams operate in highly regulated, high-availability environments, where operational excellence, reliability, and quality are non-negotiable.
Within Tech@Lilly, the Digital Core organization applies a product, platform, and reliability-first mindset, ensuring that operational capabilities scale sustainably across the enterprise.
Tech@Lilly builds and maintains capabilities using pioneering technologies like the most prominent tech companies. What differentiates Lilly IT is that we redefine what's possible through tech to advance our purpose, creating medicines that make life better for people around the world, including data-driven drug discovery, connected clinical trials, resilient enterprise platforms, and intelligent digital operations. We hire the best technology professionals from a variety of backgrounds, so they can bring an assortment of knowledge, skills, and diverse thinking to deliver creative solutions in every area of our business.
The Digital Core team leads Lilly's transformation into the Digital and AI era. They inspire digitally empowered teams to new ways of working and accelerate innovation and agility. This team powers and advances the entire company by building and maintaining world-class technology capabilities and platforms.
Lilly Capability Centre India (LCCI), Hyderabad, is Lilly's premier Global Technology Hub, harnessing data, AI, analytics, and digital solutions to revolutionize healthcare and improve patient outcomes worldwide.
The Production Reliability Engineering team is the engineering-first function that owns operations, incident command, runbook automation, and the safe evaluation of agent-assisted remediation across a multi-application production estate. The estate is deliberately diverse: it spans low-code platforms (Power Platform, Power Automate), SaaS ecosystems (Salesforce / SFDC, SharePoint), traditional enterprise stacks (Java/JVM, .NET, Node.js, Python), automation platforms (RPA — Automation Anywhere, UiPath-class tooling), data and analytics platforms (Power BI, Tableau, relational and NoSQL databases), and the integration layer that ties them together. The team works in close partnership with the engineering team that builds the agentic automation platform that increasingly reduces manual operational load.
As a Principal Production Engineer in Operations, you are the final-escalation authority within your shift and the named on-call anchor for the team. You drive root-cause analyses to engineering-grade quality before handoff to the SRE engineering practice in the same pillar, and you are the last call before the engineering lead is engaged.
What sets this seat apart from a single-stack senior engineer is the breadth of technology you operate across. The estate covers low-code platforms, SaaS ecosystems, traditional enterprise stacks, RPA and automation tooling, integration middleware, and data and analytics platforms. You are expected to debug across all of them — not by memorising every product, but by reading logs, traces, code, and configuration in any reasonable stack and isolating where it broke. Candidates who thrive in this role pick up unfamiliar tech in weeks, not quarters.
This is a senior individual-contributor role with real shift weight and real authority. The team supports continuous operations across multiple shifts, and you will anchor on-call coverage for your assigned shift while partnering with the engineering lead on cross-shift incident command.
At the principal level in operations, success is defined by named-owner posture and sustained operational outcomes:
Availability to work flexible work hours is/may be required. This team supports continuous operations and may require non-standard work hours, including some work on weekends and holidays. Appropriate adjustments in benefits will be provided for employees working non-standard hours where applicable.
This is an onsite role based in Hyderabad. Candidates should be open to working different shifts (e.g., 6 AM to 2 PM and 2 PM to 11 PM) when required to align with global delivery partners.
At Lilly, caring is not only what we do for patients. It is how we work. We believe the people who dedicate themselves to making medicines better deserve an environment that makes their lives better too, one where they are supported, respected, and given the space to do their best work. This is not just a policy. It is who we are.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form for further assistance.
Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
#WeAreLilly

We're a medicine company turning science into healing to make life better for people around the world. It all started nearly 150 years ago with a clear vision from founder Colonel Eli Lilly: "Take what you find here and make it better and better." Harnessing the power of biotechnology, chemistry and genetic medicine, our scientists are urgently advancing science to solve some of the world's most significant health challenges.
General Information and Guidelines:
When you engage with us on LinkedIn, you're agreeing to these Community Guidelines: https://e.lilly/guidelines.
If you have questions about a Lilly medicine, contact The Lilly Answers Center at 1-800-Lilly-Rx (1-800-545-5979) Monday through Friday, excluding company holidays.