
Health Futures is a Research and Incubation team working at the intersection of computer science, signal processing, machine learning, and biomedicine. We are a global and diverse team of engineers, scientists, and medical doctors who are working on next-generation Artificial Intelligence (AI) tools and methods for health and life sciences. We offer a unique and vibrant environment that features innovative academic research, enterprise software development, and real-world delivery, with close feedback loops and rapid iterations among all three, much like a lean startup. Our mission is to empower every person on the planet to live a healthier future.
We are seeking a Principal Machine Learning Engineer to accelerate our training of generative models in close collaboration with Maching Learning (ML) researchers, software engineers, and domain experts. This is a hands-on technical role focused on advancing state-of-the-art model capabilities across a variety of scientific domains and modalities. You’ll spend your time working across the stack from curriculum design, to debugging training runs, through developing new evaluation methods and high-performance inferencing – with a goal of improving all phases of our training process.
As part of Health Futures, you’ll have the opportunity to tackle everything from model training to data and evaluation pipelines. Your work will span the full spectrum of model development – training and optimizing models on the latest hardware, devising new ways to assess their capabilities, and evolving data and training workflows to maximize model utility. Beyond model training, you’ll participate in explorations of how these models can and should be used in the real world – and the systems required to successfully operate them.
At Microsoft, our mission—to empower every person and every organization on the planet to achieve more—guides how we partner with customers to deliver trusted, impactful solutions. With a growth mindset culture, we innovate responsibly and measure success by shared progress—people, teams, and customers. Join us to do meaningful work that changes the world and helps shape what’s next for everyone.
Responsibilities
Qualifications
Required Qualifications
Preferred Qualifications
#Research #healthfutures #researchsystems
Software Engineering IC5 - The typical base pay range for this role across the U.S. is USD $139,900 - $274,800 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.
Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here:
https://careers.microsoft.com/us/en/us-corporate-pay
This position will be open for a minimum of 5 days, with applications accepted on an ongoing basis until the position is filled.
Microsoft is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, color, family or medical care leave, gender identity or expression, genetic information, immigration status, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran or military status, race, ethnicity, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable local laws, regulations and ordinances. If you need assistance with religious accommodations and/or a reasonable accommodation due to a disability during the application process, read more about requesting accommodations.

Every company has a mission. What's ours? To empower every person and every organization to achieve more. We believe technology can and should be a force for good and that meaningful innovation contributes to a brighter world in the future and today. Our culture doesn’t just encourage curiosity; it embraces it. Each day we make progress together by showing up as our authentic selves. We show up with a learn-it-all mentality. We show up cheering on others, knowing their success doesn't diminish our own. We show up every day open to learning our own biases, changing our behavior, and inviting in differences. Because impact matters.
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