Job Description

Case Western Reserve University, Department of Medicine is seeking a qualified candidate to fill a postdoctoral scholar position in the laboratory of Moonsoo M. Jin, PhD. This is a one-year appointment with the possibility of renewing for an additional year.

The laboratory develops T cell immunotherapies and engineered biologics for cancer and imaging applications. Projects run from protein engineering and cell engineering through preclinical mouse models to clinical translation, and make heavy use of PET/CT imaging to measure where a biologic goes in the body.

Research areas include:

· T cell immunotherapy and biologics (e.g., T cell engager) for cancer

· Clinically applicable novel imaging markers of cancer

· Mouse models for evaluating efficacy and toxicity of cell and biologic drugs

Responsibilities and Duties

1. Design, execute, and troubleshoot independent research projects in T cell engineering, protein engineering, and molecular imaging, under the direction of the Principal Investigator.
2. Develop and perform experimental methods including mammalian and bacterial cell culture, primary human and murine T cell isolation and transduction, flow cytometry, protein expression and purification, and binding, cytotoxicity, and cytokine assays.
3. Plan and carry out preclinical mouse studies, including tumor implantation, dosing and treatment schedules, small-animal imaging, tissue collection, and endpoint analysis, in strict accordance with approved IACUC protocols.
4. Analyze, interpret, and document research results; maintain complete and accurate laboratory records and datasets suitable for audit, publication, and data sharing.
5. Prepare manuscripts for publication in peer-reviewed journals, present findings at laboratory meetings and scientific conferences, and contribute to grant applications and progress reports.
6. Collaborate with other laboratory members and with departmental and institutional core facilities, communicating data clearly and reporting results in a comprehensive manner.
7. Follow all laboratory, biosafety, and radiation safety requirements; promptly report incidents and identified hazards; and contribute to laboratory quality and safety practices.
8. Assist with training and mentoring of graduate students, undergraduates, and technical staff, and participate in professional development activities appropriate to a postdoctoral appointment.

In compliance with the City of Cleveland’s Pay Transparency Ordinance (effective October 27, 2025), the annual starting base salary range for this position is $55,000 -

$63,480. CWRU considers factors such as (but not limited to) the specific grant funding and the terms of the research grant when extending an offer. Postdocs receive

individual and family healthcare benefits, life insurance, and employee assistance.

Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities Applications requiring a reasonable accommodation for any part of the application and hiring process should contact the CWRU Office of Equity at 216.368.3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

Qualifications

Minimum Qualifications

• Doctorate (PhD, MD, or equivalent) in cancer biology, immunology, biochemistry, molecular biology, pharmacology, bioengineering, or a related discipline, completed by the start date.
• Demonstrated publication track record in peer-reviewed journals, including at least one first-author publication.
• Hands-on experience with mammalian cell culture and with laboratory animal handling.
• Excellent written and oral communication skills necessary.
• Must be eligible to work in the United States.

Equal Employment Opportunity Statement

Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.

Reasonable Accommodation Statement:

Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity by phone at 216.368.3066 or by email at equity@case.edu. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.