Successful candidates will be responsible for designing and conducting studies to develop
cancer mRNA vaccines and to investigate the role of aberrant epigenetics (DNA methylation, mRNA
N6-Methyladenosine) in cancer pathogenesis.
Areas of research in Dr. Liu’s lab include: the impact of epigenetics on cancer initiation and
progression, the regulatory function of small non-coding RNA in cancer pathogenesis, cancer
vaccines, the development of cancer mRNA vaccines, and the nanostructure-mediated drug and gene
delivery for cancer therapy (My Bibliography). Inquiries on
specific projects and other details are welcome (Dr. Liu’s phone: 216-778-3071 (O); email:
Shujun.Liu2@case.edu).
Duties/Responsibilities:
The candidate is expected to work on multiple aspects of one or more projects at any time. This
will include, but is not limited to, experimental design, implementation, and data collection and
the analysis and dissemination of research data. The individual would be expected to work
independently but also to frequently collaborate with other lab members as well as scientists at
other institutions. As an integral part of our research team, the candidate would be expected to
help us to maintain a safe and professional work environment at all times, and to actively
participate in regular group meetings.
• Treatment of cancer cell lines and patient samples.
• Performance of molecular biological studies to dissect oncogenic signaling.
• Establishment of cancer disease mouse models.
• Monitoring the transgenic mice.
• Drug administration in vivo and biological assays for the tissues and organs.
• Preparation of study reports.
• Help with drafting of publications and presentations.
• Perform other duties as assigned.
Requirement/Qualifications:
•Significant experience working with in vitro and in vivo assays for oncogenic
signaling, including gene cloning, lentivirus production/infection, chromatin
immunoprecipitation (ChIP-Seq), BRIC-qPCR/Seq, Ribo-qPCR/Seq.
• Handling of transgenic and cancer mice, including experience with IV, IM, SC and IP injections
of cells and drugs; experience with bone marrow transplantation.
• Must work well within a dynamic and team-oriented start-up environment.
• Willing to take multi-task job assignments.
Education, Experience and Preference
Ph.D. in Molecular pathology and cellular biology.
Preference will be given to applicants who have completed a PhD in a related field as well as have
enthusiasm for science, critical and independent thinking skills, and an
ambition to succeed.
In compliance with the City of Cleveland’s Pay Transparency Ordinance (effective October 27, 2025), the annual starting base salary range for this position is $55,000 - $62,652. CWRU considers factors such as (but not limited to) the specific grant funding and the terms of the research grant when extending an offer. Postdocs receive individual and family healthcare benefits, life insurance, and employee assistance.
Case Western Reserve University is an equal opportunity employer. All applicants are protected under federal and state laws and university policy from discrimination based on race, color, religion, sex, sexual orientation, gender identity or expression, national or ethnic origin, protected veteran status, disability, age and genetic information.
Reasonable Accommodation Statement:
Case Western Reserve University complies with the Americans with Disabilities Act regarding reasonable accommodations for applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity by phone at 216.368.3066 or by email at equity@case.edu Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.
