We are seeking motivated postdoctoral fellows with a track record of productivity and strong interest in cancer metabolism and immunometabolism. Applicants should have a recent doctoral degree (PhD, MD, or combined degrees), with a general background in molecular and cell biology, biochemistry, and genetics.
A Postdoctoral Research Fellow position is available to study molecular regulation of nucleotide metabolism across diverse human pathophysiological contexts. As a part of the newly established St. Jude Center for Pharmacogenomics, our laboratory aims to uncover fundamental mechanisms governing metabolic reprogramming and translate these discoveries into therapeutic strategies for human disease (Wu et al., Cell Metabolism, 2024, PMID: 38876105; Wu et al., Science, 2025, PMID: 41196949.) We employ multidisciplinary approaches, including CRISPR-based functional genomics, stable isotope tracing, metabolomics, molecular and cellular biology, biochemistry, and mouse models to investigate how nucleotide metabolism influences disease progression and treatment response.
Our laboratory is committed to creating a supportive, inclusive, and collaborative environment where trainees can thrive scientifically and professionally. Postdoctoral fellows will receive individualized mentorship, opportunities to develop independent research programs, and strong support for career advancement in academia.
St. Jude Children’s Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital’s mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude is dedicated to providing unsurpassed patient care and to advancing the health of children through biomedical research.
To apply please include a cover letter, CV and the names and contact information of three references.
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St. Jude Children’s Research Hospital is a global leader in the research and treatment of pediatric cancer and other life-threatening diseases of childhood.
Headquartered in Memphis, Tennessee, St. Jude is the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children. St. Jude has been named a top pediatric cancer hospital on U.S. News & World Report’s annual "Best Hospitals" list and named to Fortune magazine’s "100 Best Companies to Work For" list.
Research and treatments developed at St. Jude are shared to help improve the survival rate for children with cancer and other life-threatening diseases worldwide. St. Jude is recognized as one of the world’s premier pediatric research and treatment institutions with a focus on acute lymphoblastic leukemia, brain tumors and infectious diseases. With eight affiliate clinics across the country, St. Jude treats about 8,600 children each year. Beyond the United States, the institution’s St. Jude Global initiative seeks to improve health care for children with life-threatening disease worldwide.
Follow us to discover the research, scientific discoveries, clinical care and employment opportunities at St. Jude. View our career opportunities: www.stjude.org/JoinOurMission. Follow St. Jude across social media at @stjuderesearch.
If you'd like to learn about employment opportunities at ALSAC, the fundraising and awareness organization for St. Jude Children’s Research Hospital, follow St. Jude Children’s Research Hospital – ALSAC.
