The Vindigni Lab is seeking a Postdoctoral Research Associate to work on the mechanisms of DNA replication stress response to chemotherapeutics. Our group focuses on DNA replication and repair, and the roles of these pathways in cancer initiation, progression and response to chemotherapy and immunotherapy. We recently identified new pathways by which replication responds to DNA-damaging chemotherapeutics and provided insights on how to target these pathways to increase chemotherapeutic sensitivity (Tirman et al., Mol. Cell 2021; Quinet et al., Mol. Cell 2020; Lemacon et al., Nat. Comm. 2017; Thangavel et al., J. Cell Biol. 2015; Berti et al., Nat. Struct. Mol. Biol. 2013).
The Postdoctoral Research Associate will have the opportunity to acquire and develop new skills, including application of state-of-the-art imaging techniques to study perturbations in replication fork dynamics genome-wide at single-molecule resolution. They will also have the opportunity to work closely within a wide network of basic research and clinical collaborators and communicate results to the scientific community through conference presentations and peer-reviewed publications, while working in a supportive, highly collaborative and energetic environment.
In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups. The postdoctoral research associate will have opportunities to acquire and develop new skills, work closely with the PI and collaborators.
Primary Duties & Responsibilities:
Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/
For more information, please visit oncology.wustl.edu/people/faculty/Vindigni/Vindigni_Res.htmll.
Trains under the supervision of a faculty mentor, including (but not limited to):
Working Conditions:
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Salary Range:
Base pay is commensurate with experience.
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Education:
Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.
CertificationsProfessional Licenses
No specific certification/professional license is required for this position.
Work Experience:
No specific work experience is required for this position.
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
At WashU, postdoctoral appointments:
Education:
No additional education unless stated elsewhere in the job posting.
CertificationsProfessional Licenses
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
No additional work experience unless stated elsewhere in the job posting.
Skills:
Collaboration, Data Analysis, Data Interpretations, Experimentation, Laboratory Operations, Laboratory Techniques, Researching, Results Reporting, Scientific Writing
For frequently asked questions about the application process, please refer to our External Applicant FAQ
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All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
