The lab of Dr. Tommaso Cupido at St. Jude Children’s Research Hospital is looking for motivated, biology-inclined synthetic chemists to push the frontier of RNA proximity-induced pharmacology.
Applicants should have a Ph.D. in chemistry, chemical biology, or related fields, familiarity with multistep organic synthesis, and at least one first-author peer-reviewed publication (accepted or close to be).
The focus is the discovery, design and development of small-molecule modulatorsusing novel screening and compound optimization platforms,with emphasis on yet-to-be-drugged pathways and biological mechanisms that regulate RNA biology and gene expression in cancer.
The project will be conducted in the Department of Chemical Biology and Therapeutics at St. Jude Children’s Research Hospital and builds on strong investments into a world-class infrastructure in high-throughput chemical discovery and synthesis.
We offer:
- State-of-the-art, fully staffed facilities for chemistry, biophysics, biochemistry, structural biology, mass spectrometry, genomics, cell microscopy and data-driven discoveries at St Jude.
A highly collaborative and supportive research environment with premier experts in cancer biology.
Opportunities to develop expertise across chemical biology, structural, cellular and molecular biology, proteomics, and drug discovery.
Strong opportunities for scientific growth, publication, grant writing, collaboration, and career development.
Please direct queries and application packets including a cover letter, current CV, in a single PDF, to Dr. TommasoCupido( tommasocupido@stjude.org). Applicants should be ready to send three letters of reference directly to this email address upon request.
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Headquartered in Memphis, Tennessee, St. Jude is the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children. St. Jude has been named a top pediatric cancer hospital on U.S. News & World Report’s annual "Best Hospitals" list and named to Fortune magazine’s "100 Best Companies to Work For" list.
Research and treatments developed at St. Jude are shared to help improve the survival rate for children with cancer and other life-threatening diseases worldwide. St. Jude is recognized as one of the world’s premier pediatric research and treatment institutions with a focus on acute lymphoblastic leukemia, brain tumors and infectious diseases. With eight affiliate clinics across the country, St. Jude treats about 8,600 children each year. Beyond the United States, the institution’s St. Jude Global initiative seeks to improve health care for children with life-threatening disease worldwide.
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