Salary for this Role:
From £45,500 with benefits, subject to skills and experience
Job Title:
Postdoctoral Fellow - P Znamenskiy lab
Reports to:
Petr Znamenskiy
Closing Date:
19/Apr/2026 23.59 GMT
Postdoctoral Fellow - P Znamenskiy lab
Reporting to: Petr Znamenskiy, Group Leader
Contact term: This is a full-time, fixed term 4 year position on Crick terms and conditions of employment.
About us
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
About the role
The Znamenskiy lab studies the relationship between the in vivo function, synaptic organization, and molecular identity of cortical neurons. We aim to understand how connections between different neuronal cell types are organized and how this organization enables the computations they perform. To do this, we combine approaches from systems and molecular neuroscience and develop new tools to relate gene expression and connectivity with the activity of cortical neurons.
This project will investigate how different cell types that make up the cortical microcircuit respond to three-dimensional visual stimuli (https://doi.org/10.1101/2024.09.27.615442), and how the inputs onto single depth-selective neurons give rise to their response properties.
To accomplish this, this project, which you will lead on, will apply multiphoton calcium imaging to profile neuronal responses in virtual reality, correlative in situ sequencing to relate molecular identity of single neurons to their in vivo responses, and molecular connectomics to resolve the synaptic inputs of hundreds of neurons simultaneously (https://doi.org/10.1101/2025.07.16.665048)
We are seeking candidates with a PhD in Neuroscience or a related field who bring hands-on expertise in in vivo calcium imaging or electrophysiology, along with strong data analysis experience in Python and/or MATLAB. Candidates who combine quantitative skills with a collaborative mindset and an interest in research at the interface of systems and molecular neuroscience are strongly encouraged to apply.
What you will be doing
Typical activities include:
About you
You will have:
*Minimum requirement
See the full job description here.
About Working at the Crick
Our values
Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences.
We are a Disability Confident: Committed employer and want to ensure that everyone can apply and be part of our recruitment processes and so we'll make reasonable adjustments if you need them - just let us know when you apply. If you need assistance with applying (i.e., would like to apply by phone or post) please email: weronika.kucala@crick.ac.uk
Find out more about life at the Crick.
What will you receive?
At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:
Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.
We reserve the right to withdraw this advert at any given time due to the number of applications received.
The Crick is a distinctive biomedical research institute. We’re committed to advancing, promoting, and sharing understanding of human health and disease. We do that by attracting talented and ambitious people from all disciplines and backgrounds and giving them the support and freedom they need to succeed.
Inside the Crick, you’ll discover scientists working to stretch the very limits of what we know about how life works. Their research holds the key to answering fundamental questions about human health and disease. Our bold and innovative research projects bring together scientists and technicians from all disciplines in the pursuit of discovery without boundaries.
With the support of our partners, we’re bridging the gap between discovery and application to help change lives for the better. And through our dynamic structure, we’re able to develop the science leaders of tomorrow.
That’s our bold idea, tell us yours.
Cover image taken at the Crick by Thomas Angus, Imperial College London.
